Protein Alignment CG11069 and wht-8

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_499442.2
• Gene: wht-8 / 189976
• WormBaseID: WBGene00012925
• Length: 619
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 129/603 - (21%)
• Similarity: 232/603 - (38%)
• Gaps: 123/603 - (20%)

  Fly    10 LEAHNIFHTTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLD-VISRRADG 73
            |:..|:..||:         ||.  ::|.||:.....|||:|::|:.|:||..||: ::.|...|
 Worm    34 LQWRNLKVTTK---------AGR--VLLNGVSGCAVPGEVIALMGASGAGKTTLLNTLLQRNLRG 87

  Fly    74 -ATRGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHY-----TPTILSGYLKSSKVRQ 132
             ...|::|:||..:.|.: .....||.|...|:..|||.:.|..     .|...|...::::|.:
 Worm    88 LQVEGEILVNGQNIGKGV-TSVSAYVQQEDLFMGTLTVKEHLDIQAKLRLPPGTSTTARATRVNE 151

  Fly   133 VLADLALSQVAHKRVEYLNI------SEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISI 191
            |:.::.|.:....|:....|      .|.:|||...:::.:|.::..||||.|||...:..::..
 Worm   152 VMNEMLLEKPRDSRIGVPGIKKGISGGEMKRLAFATEMINNPPIIFCDEPTTGLDSHMSLQVVKT 216

  Fly   192 LSNTAKKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPL 256
            |...|.:.|..|:.::.:|.|:||...|:.:||..|.:.:.|.....:.:|...|:..|...||.
 Worm   217 LEQMALEKGKTIICTIHQPSSEVFEIFDKVVFLAQGRIAFHGAIDEAIHHFSSCGYQVPDHTNPA 281

  Fly   257 MYYL----------------CLSTVDRRSRD-------RFLESSQQIEALVERFSRETPISDAPL 298
            .|::                |....|:..:.       :.::.::.:.|:....|...|:
 Worm   282 DYFIDTLAIKPSEAEACKSRCQELCDKFEKSFYNERLTKLMDQTKDVRAMTPHHSATYPV----- 341

  Fly   299 NNMGSGKVPLAYGKPGELKVWVMLYLKLLASTFSCGLVGMKTLFLRLLLLPLALSILWAFYTDVG 363
                              .::.:.|..:|.:..:..:  ||...::.|.:.|.:..|  || .:.
 Worm   342 ------------------LLYALFYRYMLDNIRNPAI--MKAKLIQKLFMGLFIGTL--FY-GLE 383

  Fly   364 DDSHGFFTKNGMILNILGLSYGCGILTTISLFPIWRKKFSQDTP-------EGLYSGTTLLIAYN 421
            .|..|..:..|      .|.|....||..::|.| :.....|.|       :.:|..:...||..
 Worm   384 TDQDGLASYKG------ALFYYISELTYSTIFGI-QAFMPADYPPLVREYDDRIYPISAYYIAKI 441

  Fly   422 SVSIPFSAVSAVIASCVVYPLLLDVKYNNGTVFAYLLVALWSSF-VLAEQL-----------TIA 474
            ...:|...|..:|.                .|.:|.||...|.| |...|:           .:.
 Worm   442 CSFLPIFTVDGIIL----------------VVSSYFLVGFPSDFGVFLRQIFTCMAIEWNVAALG 490

  Fly   475 FLLVVKVP-FNAAIAVTYVLVISIALASGTVRSFKGLQPWLQDNTKGTHTRYASSLLHSIAFQSR 538
            ..:....| :..|:.||..|:...:|..|...:...:..|:......:..||....|....||..
 Worm   491 IAVCATAPSYAIAVTVTGPLLTVFSLTGGLFTNIAEMPAWINWVQYLSWFRYGYESLVVNQFQHD 555

  Fly   539 KL-NCTPTASV---ICPK 552
            :. |.|..|::   :|.|
 Worm   556 QFANITCNANMNEQLCEK 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	63/230 (27%)
		ABC2_membrane	364..515	CDD:473876	33/170 (19%)
wht-8	NP_499442.2	3a01204	22..615	CDD:273361	129/603 (21%)