Protein Alignment CG11069 and wht-2

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_502164.1
• Gene: wht-2 / 178069
• WormBaseID: WBGene00007513
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 138/568 - (24%)
• Similarity: 234/568 - (41%)
• Gaps: 136/568 - (23%)

  Fly    13 HNIFHTTEVDGGGCFNGAGNSALVLKGVNLTVHSGEVMAILGSKGSGKRALLD-VISRRADG-AT 75
            |||....|..|          ..:|:.|:.....|:::|::|:.|:||..||: ::||...| .|
 Worm    37 HNISIHAEKSG----------KQILENVSGIAKPGQLLALMGASGAGKTTLLNMLLSRNLRGLET 91

  Fly    76 RGQVLLNGSPLSKALFQQRCGYVTQSCTFVPGLTVAQTLHYTPTI-LSG--YLKSSKVRQVLADL 137
            .|.|.:||..|.:.: ....||..|...||..|||.:.|.....: ::|  ..:..:|..|::.|
 Worm    92 SGSVKVNGHELGRGI-TAISGYAQQDELFVGTLTVKEYLDIQAKLRVNGDSEKRRRRVGNVMSQL 155

  Fly   138 ALSQVAHKRV------EYLNISEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTA 196
            .|.:..:.|:      :.::..|.|||....:|:.:|.:|..||||.|||...|..::.:|||.|
 Worm   156 GLYKCQNTRIGTIGGQKGISGGEMRRLTFACELLSNPSILFCDEPTTGLDSFMAESVVQVLSNLA 220

  Fly   197 KKTGCGILLSLEKPRSDVFPFLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYLC 261
             |:|..::.::.:|.|.::...||.:|:..|...:.|..|..:::|...||.||:..||....:.
 Worm   221 -KSGRTVICTIHQPSSQLYLMFDRVMFMAGGKTAFLGSPRDAIQFFEDAGFACPRNFNPADLIIH 284

  Fly   262 LSTVDRRSRDRFLESSQQIEALVERFSRETPISDAPLNNMGSGKVPLAYG--------KPGEL-K 317
            ...|.....|:   ..|:||.:..:|           .|...|:. |.:|        :|.|. |
 Worm   285 TLAVMPNEEDK---CRQRIEVIYTKF-----------QNSSYGRT-LKFGVEKSDEGQRPSERHK 334

  Fly   318 VWVMLYLKLL----------------ASTFSCGLVGMKTLFLRLLLLPLALSILWAFYTDVGDDS 366
            ..::..:..|                |......::|   ||:.||.|...|:            |
 Worm   335 TGILTQIGALLERSAIDTWRNPSLTRAKVIQKSIMG---LFIGLLYLQSPLT------------S 384

  Fly   367 HGFFTKNGMILNIL-GLSYGC--GILTTISL-FPIWRKKFSQDTPEGLYSGTTLLIAYNSVSIPF 427
            .|....||.:..:: .|:|..  |||..:.. ||:    .|::..:|||
 Worm   385 IGISNLNGALFYLVCELTYSTIFGILNFLPADFPL----VSREYHDGLY---------------- 429

  Fly   428 SAVSAVIASCVVY-PLLLDVKYNNGTVFAYLLVALW----SSFV-----------LAEQLTIAFL 476
            |..|..:|.|:.| ||..    .:|.:.  |||:.|    ||.:           |.||.:.|..
 Worm   430 SVFSYYVARCLSYLPLFT----ADGLIM--LLVSYWMVGFSSSITQVLYACLIAFLIEQSSSACG 488

  Fly   477 LVV-----KVPFNAAIAVTYVLVISIALASGTVRSFKGLQP----WLQ 515
            :::     .:|...:.|...:.::|:   :|.:.:..|..|    |:|
 Worm   489 IMISCISPSLPIAMSTAGPMLTLLSL---TGGLYANVGALPSYISWIQ 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	64/228 (28%)
		ABC2_membrane	364..515	CDD:473876	40/179 (22%)
wht-2	NP_502164.1	3a01204	44..610	CDD:273361	135/561 (24%)