Protein Alignment CG11069 and Abcg8

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_569098.2
• Gene: Abcg8 / 155192
• RGDID: 620300
• Length: 672
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 161/616 - (26%)
• Similarity: 263/616 - (42%)
• Gaps: 120/616 - (19%)

  Fly    35 LVLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRADGA--TRGQVLLNGSPLSKALFQQRCGY 97
            |.::.::..|.||:::||:||.|.|:..|||||:.|..|.  ..||:.:||.|.:..|.|:...:
  Rat    86 LGIRNLSFKVRSGQMLAIIGSAGCGRATLLDVITGRDHGGKMKSGQIWINGQPSTPQLIQKCVAH 150

  Fly    98 VTQSCTFVPGLTVAQTLHY-----TPTILSGYLKSSKVRQVLADLALSQVAHKRVEYLNI----- 152
            |.|....:|.|||.:||.:     .|...|...:..:|..|:|:|.|.|.|:.||....:
  Rat   151 VRQQDQLLPNLTVRETLTFIAQMRLPKTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSG 215

  Fly   153 SEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPF 217
            .|.||::||:||:.:|.:|:|||||.|||..:|:.|:..||..||.... :|:||.:||||:|..
  Rat   216 GERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLAKGNRL-VLISLHQPRSDIFRL 279

  Fly   218 LDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYLCLSTVDRRSRDRFLESSQQIEA 282
            .|..|.:..|..:|.|..:.|::||..||:|||:..||..:|:.|:::||||:::.:.:.::...
  Rat   280 FDLVLLMTSGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDLTSIDRRSKEQEVATMEKARL 344

  Fly   283 LVERFSRETPISD-----APLNNMGSGKVPLAY--------GKPGELKVWVMLYLKLLASTFSCG 334
            |...|..:....|     |...::.:|...::.        |...||...:..:..|:....|..
  Rat   345 LAALFLEKVQGFDDFLWKAEAKSLDTGTYAVSQTLTQDTNCGTAAELPGMIQQFTTLIRRQISND 409

  Fly   335 LVGMKTLFLRLLLLPLALSILWAFYTDVGDDSHGFFTKNGMILNILG-LSYGCGILTTISLFPIW 398
            ...:.|||:                       ||  .:..::..|:| |.||
  Rat   410 FRDLPTLFI-----------------------HG--AEACLMSLIIGFLYYG------------- 436

  Fly   399 RKKFSQDTPEGLYSGTTLLIAYNSVSIPFSAVSAVIASC-----VVYPLLLDVKYNNGTVF---- 454
                ..|.|........||....:: |||:.:..|::.|     ::|..|.|..|..|..|
  Rat   437 ----HADKPLSFMDMAALLFMIGAL-IPFNVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKV 496

  Fly   455 --------AYLLVALWSSFVLA------EQLTIAFLLVVKVPF---NAAIAVTYVLVI------- 495
                    ||:::.....:.|.      |...:.|:|:..|.|   ..|:|.:.:|..
  Rat   497 LGELPEHCAYVIIYGMPIYWLTNLRPGPELFLLHFMLLWLVVFCCRTMALAASAMLPTFHMSSFC 561

  Fly   496 ------SIALASGTVRSFKGL---QPWLQDNTKGTHTRYASSLLHSIAFQSRKLNCTPTASVICP 551
                  |..|.:|.:.:...|   ..|:   :|.:..|:..|.|..|.|... :..|...::...
  Rat   562 CNALYNSFYLTAGFMINLNNLWIVPAWI---SKMSFLRWCFSGLMQIQFNGH-IYTTQIGNLTFS 622

  Fly   552 KPADFMHERLGLPDPD----ETIDVAASCAF 578
            .|.|.|...:.|....    ..|.:..||.|
  Rat   623 VPGDAMVTAMDLNSHPLYAIYLIVIGISCGF 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	78/209 (37%)
		ABC2_membrane	364..515	CDD:473876	38/193 (20%)
Abcg8	NP_569098.2	ABCG_White	60..295	CDD:213201	78/209 (37%)
		3a01204	88..662	CDD:273361	160/614 (26%)