DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11069 and Abcg5

DIOPT Version :10

Sequence 1:NP_651307.2 Gene:CG11069 / 42976 FlyBaseID:FBgn0039244 Length:604 Species:Drosophila melanogaster
Sequence 2:NP_446206.2 Gene:Abcg5 / 114628 RGDID:620298 Length:652 Species:Rattus norvegicus


Alignment Length:598 Identity:176/598 - (29%)
Similarity:293/598 - (48%) Gaps:65/598 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 VLKGVNLTVHSGEVMAILGSKGSGKRALLDVIS--RRADGATRGQVLLNGSPLSKALFQQRCGYV 98
            :||.|:|.:.||:.|.||||.||||..|||.||  .|..|...|:|.:||..|.:..||....|:
  Rat    69 ILKDVSLYIESGQTMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFVNGCELRRDQFQDCVSYL 133

  Fly    99 TQSCTFVPGLTVAQTLHYTPTILSGYLKSS-------KVRQVLADLALSQVAHKRVEYLNI---- 152
            .||..|:..|||.:||.||..:.   |:||       ||..||.:|:||.||.:.:...|.    
  Rat   134 LQSDVFLSSLTVRETLRYTAMLA---LRSSSADFYDKKVEAVLTELSLSHVADQMIGNYNFGGIS 195

  Fly   153 -SEARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFP 216
             .|.||::|..||::||.:::|||||.|||.::|..::.:|...|::... :::::.:|||::|.
  Rat   196 SGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANHIVLLLVELARRNRI-VIVTIHQPRSELFH 259

  Fly   217 FLDRALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYLCLSTVDRRSRDRFLESSQQIE 281
            ..|:...|..|.:|:.|....||.:|:..|:|||:..||..:|:.|::||.:||:|.:|:.::::
  Rat   260 HFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMDLTSVDTQSREREIETYKRVQ 324

  Fly   282 ALVERFSRETPISDAPLNNMGSGK----VPLAYGK----PGELKVWVMLYLKL--LASTFSCGLV 336
            .|...| |::.|....|.|:...:    :|:...|    ||       ::.||  |....:..|:
  Rat   325 MLESAF-RQSDICHKILENIERTRHLKTLPMVPFKTKNPPG-------MFCKLGVLLRRVTRNLM 381

  Fly   337 GMKTLFLRLLLLPLALSILWAFYT----------DVGDDSHGFFTKNGMILNILGLSYGCGILTT 391
            ..|.:.:..|:..|.:.:...||.          .|.|       :.|::..::|.:...|:|..
  Rat   382 RNKQVVIMRLVQNLIMGLFLIFYLLRVQNNMLKGAVQD-------RVGLLYQLVGATPYTGMLNA 439

  Fly   392 ISLFPIWRKKFSQDTPEGLYSGTTLLIAYNSVSIPFSAVSAVIASCVVYPLLLDVKYNNGTVFAY 456
            ::|||:.|....|::.:|||....:|:||...::|||.|:.||.|.|.|..|  ..|.....|.|
  Rat   440 VNLFPMLRAVSDQESQDGLYQKWQMLLAYVLHALPFSIVATVIFSSVCYWTL--GLYPEVARFGY 502

  Fly   457 LLVALWSSFVLAEQLTIAFLLVVKVPFNAAIAVTYVLVIS-IALASGTVRSFKGLQPWLQDNTKG 520
            ...||.:..::.|.||:..|.:|:.| |...::..:|.|| :.:.||.:|:.:.:...|:.....
  Rat   503 FSAALLAPHLIGEFLTLVLLGMVQNP-NIVNSIVALLSISGLLIGSGFIRNIEEMPIPLKILGYF 566

  Fly   521 THTRYASSLLHSIAFQSRKLNCTPTASVICPKPADFMHERLGLPDPDETIDVAASCAFAVGLAAF 585
            |..:|...:|....|......|..:.:.:...|...|.:.:..        :..:|..|......
  Rat   567 TFQKYCCEILVVNEFYGLNFTCGGSNTSVPNNPMCSMTQGIQF--------IEKTCPGATSRFTT 623

  Fly   586 NMLVYLFPMPRCV 598
            |.|:....:|..|
  Rat   624 NFLILYSFIPTLV 636

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11069NP_651307.2 ABCG_White 15..233 CDD:213201 80/210 (38%)
ABC2_membrane 364..515 CDD:473876 44/151 (29%)
Abcg5NP_446206.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..30
ABCG_White 50..276 CDD:213201 80/210 (38%)
3a01204 61..646 CDD:273361 176/598 (29%)
Blue background indicates that the domain is not in the aligned region.

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