Protein Alignment CG11069 and abcg8

DIOPT Version :10

• Sequence 1: NP_651307.2
• Gene: CG11069 / 42976
• FlyBaseID: FBgn0039244
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_031758486.1
• Gene: abcg8 / 100498405
• XenbaseID: XB-GENE-981625
• Length: 682
• Species: Xenopus tropicalis
• Alignment Length: 630
• Identity: 169/630 - (26%)
• Similarity: 282/630 - (44%)
• Gaps: 107/630 - (16%)

  Fly    37 LKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRADGA--TRGQVLLNGSPLSKALFQQRCGYVT 99
            :|.:|:.|.||:::|::|:.|.||.:|||:|:.:.:|.  ..||:|:||...:|...::...:|.
 Frog    90 MKNINVKVTSGQMLAVIGNTGCGKTSLLDIITCKDEGGKIKSGQILINGKVSTKHRVKKCVAHVR 154

  Fly   100 QSCTFVPGLTVAQTLHY-----TPTILSGYLKSSKVRQVLADLALSQVAHKRV-----EYLNISE 154
            |....:|.|||.:||.:     .|...|...:..:|..|:|:|.|.|.|:.:|     ..::..|
 Frog   155 QDDQLLPHLTVRETLTFIAKLRLPKSYSEEQRRRQVEDVIAELRLRQCANTKVGNTYTRGVSGGE 219

  Fly   155 ARRLAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLD 219
            .||::||:||:.:|.:|:|||||.|||..:|:.|:..||..|:.... :|||:.:||||:|...|
 Frog   220 RRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVITLSRLARGNRL-VLLSIHQPRSDIFQLFD 283

  Fly   220 RALFLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYLCLSTVDRRSRDRFLESSQQIEALV 284
            ..|.|..|..:|||..:.|:|||..||:|||:..||..:|:.|:::|:|:::|..||.::..:|.
 Frog   284 LVLLLSSGATIYSGTAKDMVEYFSSIGYPCPRYSNPADFYVDLTSIDQRNKERETESLERTRSLA 348

  Fly   285 ERFSRETPISD--------------APLNNMGSGKVPL-AYGKPGELKVWVMLYLK--------L 326
            |.|..:...||              .|.|.  |..:|: |:.|..::|...|..|.        |
 Frog   349 EIFWEKVKDSDDFLWKPPGEANKNITPTNT--SINLPVSAHEKAIKIKNSDMDQLPRGLHQFSVL 411

  Fly   327 LASTFSCGLVGMKTLFLR-LLLLPLALSILWAFYTDVGDDSHGFFTKNGMILNIL--GLSYGCGI 388
            |....|..|..:.||.:. ...|.:||.|.:.:|   |..::....::.:.|..:  .|:....:
 Frog   412 LRRHVSNDLRDLSTLLIHGFEALVMALLIGFLYY---GQGNNQLSIQDSIALLFMKGSLTPFAVV 473

  Fly   389 LTTISLFPIWRKKFSQDTPEGLYSGTTLLIAYNSVSIPFSAVSAVIASCVVYPL----------L 443
            |..::.....|.....|..:||||.|....|.....:|......:.....:|.|          |
 Frog   474 LDVVAKCHSERAMLYHDLEDGLYSVTPYFFAKVIGELPEHFAFVIFYGVPIYWLANLNPHPECFL 538

  Fly   444 LDVKYNNGTVFAYLL--------VALWSSFVLAEQLTIAFLLVVKVPFNAAIAVTYVLVISIALA 500
            |:        ||.||        :|||.|.:|......:||      .||....:|       |.
 Frog   539 LN--------FALLLLIVYCSRAMALWMSALLPTLQMSSFL------SNAIFTSSY-------LT 582

  Fly   501 SGTVRSFKGLQP---WLQDNTKGTHTRYASSL------LHSIAFQSRKLNCTPTASVICPKPADF 556
            .|.:...:.|..   |:.         |.|.|      |..:.|...... .|..::....|...
 Frog   583 GGFIIRLENLWTVPYWIS---------YVSFLRWGFEGLMQVQFTDLSYK-VPVGNITITIPGTA 637

  Fly   557 MHERLGLPDPDETIDVAASCAFAVGLAAFNMLVYLFPMPRCVRQK 601
            :...:.:    ::..:.||....:|:.|..:::|...: |.::||
 Frog   638 IISNMEM----DSHPLYASYLVLIGIIAGFLVLYYLSL-RFIKQK 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	74/207 (36%)
		ABC2_membrane	364..515	CDD:473876	34/173 (20%)
abcg8	XP_031758486.1	3a01204	61..672	CDD:273361	166/623 (27%)