DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11069 and abcg1

DIOPT Version :9

Sequence 1:	NP_651307.2	Gene:	CG11069 / 42976	FlyBaseID:	FBgn0039244	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_002942182.2	Gene:	abcg1 / 100496811	XenbaseID:	XB-GENE-996335	Length:	664	Species:	Xenopus tropicalis

Alignment Length:	579	Identity:	133/579 - (22%)
Similarity:	247/579 - (42%)	Gaps:	43/579 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 VLKGVNLTVHSGEVMAILGSKGSGKRALLDVISRRADGATRGQVLLNGSPLSKALFQQRCGYVTQ 100
            :|||::...|.||:.||:|..|:||..|:::::...:...:|:||:||.|.....|::...|:.|
Frog    99 LLKGISGKFHCGELAAIMGPSGAGKSTLMNILAGYRETGMKGEVLINGQPRDLRSFRKVSCYIMQ 163

  Fly   101 SCTFVPGLTVAQTLHYTPTILSGYLK--------SSKVRQVLADLALSQVAHKRVEYLNISEARR 157
            ....:|.|||.:.:     ::|.:||        ...|:::|..|.|...|..|...|:..:.:|
Frog   164 DDMLLPHLTVQEAM-----MVSAHLKLQEKDEGRKEMVKEILTALGLLPCADTRTGSLSGGQRKR 223

  Fly   158 LAIGIQLVRDPVMLLLDEPTHGLDPLSAYLLISILSNTAKKTGCGILLSLEKPRSDVFPFLDRAL 222
            |||.::||.:|.::..||||.|||..|.:.::|::.:.| :.|..|:.::.:|.:.:|...|:..
Frog   224 LAIALELVNNPPVMFFDEPTSGLDSSSCFQVVSLMKSLA-QGGRNIICTIHQPSAKLFELFDQLY 287

  Fly   223 FLCLGGVVYSGGTRAMLEYFHGIGFPCPQLENPLMYYLCLSTVDRRSRDRFLESSQQIEALVERF 287
            .|..|..:|.|....::.|...:|..||...||..:.:.:::.:...::..|     :.|:.:..
Frog   288 VLSQGQCIYRGKVSNLVPYLRVLGLNCPTYHNPADFIMEVASGEYGDQNPHL-----VRAVQDNL 347

  Fly   288 SRETPISDAPLNNMGSGKVPLAYGKPGELKVWVMLYLKLLASTFSCGLVGMKTLFLRLL----LL 348
            ....|..|....|..|   ||.:.:|.|............||..:...:..|..|:.::    |.
Frog   348 CEVEPKRDLCGENEQS---PLMWHRPDEDPSPTEGCHSFSASCLTQFCILFKRTFINIMRDSVLT 409

  Fly   349 PLALS-------ILWAFYTDVGDDSHGFFTKNG-MILNILGLSYGCGILTTISLFPIWRKKFSQD 405
            .|.::       ::...|..:|:::....:.:| :..::|.|.: ..::.|:..||:....|.::
Frog   410 HLRITSHIGIGILIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMF-AALMPTVLTFPLEMGVFLRE 473

  Fly   406 TPEGLYSGTTLLIAYNSVSIPFSAVSAVIASCVVYPLLLDVKYNNGTVFAYLLVALWSSFVLAEQ 470
            .....||.....:|.....:||..:..|....:||.:   ....:..:...|..||.:...|..|
Frog   474 HLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWM---TSQPSDALRFILFAALGTMTSLVAQ 535

  Fly   471 LTIAFLLVVKVPFNAAIAVTYVLVISIALASGTVRSFKGLQPWLQDNTKGTHTRYA--SSLLHSI 533
            .....:.........|..|..|..|.:.|.||...||..:..:||..:..::.||.  ..:|...
Frog   536 SLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPSYLQWMSYMSYVRYGFEGVILSIY 600

  Fly   534 AFQSRKLNCTPTASVICPKPADFMHERLGLPDPDETIDVAASCAFAV--GLAAFNMLVY 590
            ......|:|....:....|....:.| |.:.|....:|......|.|  .|.|:.:|.|
Frog   601 GLDREDLHCEKDETCHFQKSEAILKE-LDVEDAKLYLDFIILGVFFVTLRLTAYFVLKY 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11069	NP_651307.2	ABCG_White	15..233	CDD:213201	61/204 (30%)
		CcmA	31..302	CDD:224054	73/273 (27%)
		ABC2_membrane	364..515	CDD:304374	29/151 (19%)
abcg1	XP_002942182.2	3a01204	59..664	CDD:273361	133/579 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010