Protein Alignment CG31121 and ABCG1

DIOPT Version :9

• Sequence 1: NP_733058.1
• Gene: CG31121 / 42975
• FlyBaseID: FBgn0051121
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_024307909.1
• Gene: ABCG1 / 9619
• HGNCID: 73
• Length: 786
• Species: Homo sapiens
• Alignment Length: 595
• Identity: 122/595 - (20%)
• Similarity: 243/595 - (40%)
• Gaps: 94/595 - (15%)

  Fly   261 QVDGGGGGMGYDYNEARL----YGSSRQYGNGNGHNPGSRKQSGMGLIYPNIQVHCLDVNPCLRG 321
            ||.||...:|......::    :|:.|.||.|   .||...:.|    |..:          |:|
Human   164 QVQGGPHHLGVVAISGKVLSAAHGAGRAYGWG---FPGDPMEEG----YKTL----------LKG 211

  Fly   322 VSMQAKAGDLFAIMATSQREGSALAECLAGLTER-LGGEILINGQQVSRRGLRELCSYVPALEVS 385
            :|.:..:|:|.|||..|....|.|...|||..|. :.|.:||||.....|..|::..|:  ::..
Human   212 ISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYI--MQDD 274

  Fly   386 SLDPRMSVQCTLNFHAALRGPIDRSDLEERMDVLIEDLGLNTVRASNVSTLTHSEKQRLSVACQL 450
            .|.|.::||..:...|.|:.........|.:..::..|||.:...:...:|:..:::||::|.:|
Human   275 MLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALEL 339

  Fly   451 LAQSSLLILDQVTSNMDIFDTFFLVEYLRQWCSGGRIVIMTLQPPTFEILSMCSGVLLLSGGRTV 515
            :....::..|:.||.:|....|.:|..::....|||.:|.|:..|:.::..:...:.:||.|:.|
Human   340 VNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCV 404

  Fly   516 FSGSRADLPRHMGELGYPCPPFKNPADYYLDLVTLDDLSAAAMLESSARIESLANA--------- 571
            :.|...:|..::.:||..||.:.||||:.:::.:.:.....:.|..:.| |.:.::
Human   405 YRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVR-EGMCDSDHKRDLGGD 468

  Fly   572 -------WDQINSE-------PPLAAPPASLPN-FTMKAGFFGQISALIKRFAGYKQPGSLLTWI 621
                   |.:.:.|       ..|....:|:.. .:..|....|...|.||........|:||.:
Human   469 AEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHL 533

  Fly   622 SKLIAAAVLSLFIGCIFWDVPASDPQLSYHDRLGYHHCVMVLVYWPLVMLTIRDTQEDRRHAERD 686
             ::.:...:.|.||.::..:.....::..:.  |:....|:.:.:..:|.|:         ....
Human   534 -RITSHIGIGLLIGLLYLGIGNEAKKVLSNS--GFLFFSMLFLMFAALMPTV---------LTFP 586

  Fly   687 IRLGLYTR---------SLYIIVQSLLG-----LFP----SLCIWLAYLLPAHSMAGLYTYSNSS 733
            :.:|::.|         ..|.:.:::..     :||    |:..|:.              |..|
Human   587 LEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMT--------------SQPS 637

  Fly   734 DTGIYLYMGYMLLYLTLI-QTLALFCAHLLPCKVSASIVNGLISLAVAAVGGYLVHPQNLAQFWS 797
            |...::....:....:|: |:|.|...........|:.|..:.::.|....|:.|....:..:..
Human   638 DAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQ 702

  Fly   798 WLQFVSPERW 807
            |:.::|..|:
Human   703 WMSYISYVRY 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31121	NP_733058.1	P-loop_NTPase	319..518	CDD:304359	54/199 (27%)
		cbiO	319..491	CDD:130234	48/172 (28%)
		ABC2_membrane	621..809	CDD:279410	29/206 (14%)
ABCG1	XP_024307909.1	3a01204	202..786	CDD:273361	110/554 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141406
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750