DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31121 and ABCG22

DIOPT Version :9

Sequence 1:	NP_733058.1	Gene:	CG31121 / 42975	FlyBaseID:	FBgn0051121	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_568169.1	Gene:	ABCG22 / 830541	AraportID:	AT5G06530	Length:	751	Species:	Arabidopsis thaliana

Alignment Length:	756	Identity:	156/756 - (20%)
Similarity:	292/756 - (38%)	Gaps:	155/756 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 SSGYDSSDNETTRSRVPPNLRKYRSESDFRAIGGMPHSRPESRAQIGGGGVPMAALRQANSR--- 221
            :||...:.:|.....|..::|......|   ..|:|.:.|   |.:||||    .|.:.:||
plant     9 ASGLARTRSEQLYETVAADIRSPHGSMD---ANGVPATAP---AAVGGGG----TLSRKSSRRLM 63

  Fly   222 -----ASIAVGQHHHQMQQHQQQYGKHYGHRSHSEADLLGAGLSQVDGGGGGMGYDYNEARL--- 278
                 .|...|.|..:.:..|.        :...|....||.||:......|:.:.:....:
plant    64 GMSPGRSSGAGTHIRKSRSAQL--------KLELEEVSSGAALSRASSASLGLSFSFTGFAMPPE 120

  Fly   279 -YGSSRQYGNG----NGHNPGSRKQSGMGLIYPNIQ--------VHCLDV--------------N 316
             ...|:.:.:.    .....|.:|        |..|        :...||              .
plant   121 EISDSKPFSDDEMIPEDIEAGKKK--------PKFQAEPTLPIFLKFRDVTYKVVIKKLTSSVEK 177

  Fly   317 PCLRGVSMQAKAGDLFAIMATSQREGSALAECLAGLTER--LGGEILINGQQVSRRGLRELCSYV 379
            ..|.|:|.....|::.|:|..|....:.|...|||...:  .||.:..|.:..|:. |:....:|
plant   178 EILTGISGSVNPGEVLALMGPSGSGKTTLLSLLAGRISQSSTGGSVTYNDKPYSKY-LKSKIGFV 241

  Fly   380 PALEVSSLDPRMSVQCTLNFHAALRGP--IDRSDLEERMDVLIEDLGL-----NTVRASNVSTLT 437
            ...:|  |.|.::|:.||.:.|.||.|  :.|...::|...:|::|||     ..:..:.|..::
plant   242 TQDDV--LFPHLTVKETLTYAARLRLPKTLTREQKKQRALDVIQELGLERCQDTMIGGAFVRGVS 304

  Fly   438 HSEKQRLSVACQLLAQSSLLILDQVTSNMDIFDTFFLVEYLRQWCSGGRIVIMTLQPPTFEILSM 502
            ..|::|:|:..:::...|||:||:.||.:|.......:..|......|:.||.|:..|:..:...
plant   305 GGERKRVSIGNEIIINPSLLLLDEPTSGLDSTTALRTILMLHDIAEAGKTVITTIHQPSSRLFHR 369

  Fly   503 CSGVLLLSGGRTVFSGSRADLPRHMGELGYPCPPF--KNPADYYLDLV--TLDDLSAAAMLESSA 563
            ...::||..|..::.|..::...:...:|  |.|.  .|||::.|||.  .::|:|..:.|:...
plant   370 FDKLILLGRGSLLYFGKSSEALDYFSSIG--CSPLIAMNPAEFLLDLANGNINDISVPSELDDRV 432

  Fly   564 RIESLANAWDQINSEPPLAAPPASLPNFTMKAGFFGQI---------------------SALIKR 607
            ::   .|:..:..:..|   .||::..:.::| :..::                     |..:||
plant   433 QV---GNSGRETQTGKP---SPAAVHEYLVEA-YETRVAEQEKKKLLDPVPLDEEAKAKSTRLKR 490

  Fly   608 FAG---------------YKQPGSLLTW--ISKLIAAAVLSLFIGCIFWDVPASDPQLSYHDRLG 655
            ..|               .::.....:|  ::::::.||:   :|.::|......| :...|:.|
plant   491 QWGTCWWEQYCILFCRGLKERRHEYFSWLRVTQVLSTAVI---LGLLWWQSDIRTP-MGLQDQAG 551

  Fly   656 YHHCVMVLVYWPL--VMLTIRDTQEDRRHAERDIRLGLYTRSLYIIVQSLLGL-----FPSLCIW 713
            .  ...:.|:|..  |...|....::|....::....:|..|.|.:.::...|     .|||
plant   552 L--LFFIAVFWGFFPVFTAIFAFPQERAMLNKERAADMYRLSAYFLARTTSDLPLDFILPSL--- 611

  Fly   714 LAYLLPAHSMAGLYTYSNSSDTGIYLYMGYMLLYLTLIQTLALFCAHLLPCKVSASIVNGLISLA 778
              :||..:.|.||    ..|....:|.|..:.|.:...|.|.|....:|.....|:.:..:..:.
plant   612 --FLLVVYFMTGL----RISPYPFFLSMLTVFLCIIAAQGLGLAIGAILMDLKKATTLASVTVMT 670

  Fly   779 VAAVGGYLVHPQNLAQFWSWLQFVS----PERWLLPVLVQD 815
            ....||:.|  :.:..|.||::::|    ..:.||.|..||
plant   671 FMLAGGFFV--KKVPVFISWIRYLSFNYHTYKLLLKVQYQD 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31121	NP_733058.1	P-loop_NTPase	319..518	CDD:304359	54/207 (26%)
		cbiO	319..491	CDD:130234	49/180 (27%)
		ABC2_membrane	621..809	CDD:279410	40/198 (20%)
ABCG22	NP_568169.1	PLN03211	112..748	CDD:215634	129/635 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910