DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31121 and ABCG18

DIOPT Version :9

Sequence 1:	NP_733058.1	Gene:	CG31121 / 42975	FlyBaseID:	FBgn0051121	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_191071.1	Gene:	ABCG18 / 824677	AraportID:	AT3G55110	Length:	708	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	124/570 - (21%)
Similarity:	246/570 - (43%)	Gaps:	80/570 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 VNPCLRGVSMQAKAGDLFAIMATSQREGSALAECLAG--LTERLGGEILINGQQV-SRRGLRELC 376
            |...|..::.:|:.|::.|::..|....|.|.:.|||  ..:.|.|.:.:||::| ..|.|:.:.
plant    88 VKTLLDDITGEARDGEILAVLGGSGAGKSTLIDALAGRVAEDSLKGTVTLNGEKVLQSRLLKVIS 152

  Fly   377 SYVPALEVSSLDPRMSVQCTLNFHAALRGP--IDRSDLEERMDVLIEDLGLNTVRASNVSTLTH- 438
            :||  ::...|.|.::|:.||.|.:..|.|  :.:|...||::.||:.|||.....:.:....|
plant   153 AYV--MQDDLLFPMLTVKETLMFASEFRLPRSLPKSKKMERVETLIDQLGLRNAADTVIGDEGHR 215

  Fly   439 ----SEKQRLSVACQLLAQSSLLILDQVTSNMDIFDTFFLVEYLRQWCSGGRIVIMTLQPPTFEI 499
                .|::|:|:...::....||.||:.||.:|..:.|.:|:.|::....|.:|||::..|:..|
plant   216 GVSGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTNAFMVVQVLKRIAQSGSVVIMSIHQPSARI 280

  Fly   500 LSMCSGVLLLSGGRTVFSGSRADLPRHMGELGYPCPPFKNPADYYLDLVTLDDLSAAAMLESSAR 564
            :.:...:::||.|::||:||...||......|.|.|..:|..::.||::.  :|..::  |.:..
plant   281 IGLLDRLIILSHGKSVFNGSPVSLPSFFSSFGRPIPEKENITEFALDVIR--ELEGSS--EGTRD 341

  Fly   565 IESLANAWDQ-----------INSEPPLAAPPASLPNFTMKAGFFGQISALIKRFAGYKQPGSLL 618
            :......|.|           ::.:..:|   ||:....:.:|..|.....::..:.|..|....
plant   342 LVEFNEKWQQNQTARATTQSRVSLKEAIA---ASVSRGKLVSGSSGANPISMETVSSYANPPLAE 403

  Fly   619 T----------WI-------SKLIAAAVLSLFIGCIFWDVPASDPQLSYHDRLGYHHCVMVLVYW 666
            |          ||       .::....|..|.:..::|.:. :.|: ...:|:|:....|..:::
plant   404 TFILAKRYIKNWIRTPELIGMRIGTVMVTGLLLATVYWRLD-NTPR-GAQERMGFFAFGMSTMFY 466

  Fly   667 ------PLVMLTIRDTQEDRRHAERDIRLGLYTRSLYIIVQSLLGLFPSLCIWLAYLLPAHSMAG 725
                  |:.:       ::|....|:.....|..|.|:|..:|:.|...|.:.:|:........|
plant   467 CCADNIPVFI-------QERYIFLRETTHNAYRTSSYVISHALVSLPQLLALSIAFAATTFWTVG 524

  Fly   726 LYTYSNSSDTGIYLYMGYMLLYLTLI---QTLALFCAHLLPCKVSASIVNGLISLAVAAVGGYLV 787
            |       ..|:..:..|.|:.....   .::..|.:.|:|..:.:.:|..........:||:.:
plant   525 L-------SGGLESFFYYCLIIYAAFWSGSSIVTFISGLIPNVMMSYMVTIAYLSYCLLLGGFYI 582

  Fly   788 HPQNLAQFWSWLQFVSPERWLLPVLVQDEYSAETLSNSAGLQLCRNKQVQ 837
            :...:..:|.|..::|        |::..|.|..::.......|..|.||
plant   583 NRDRIPLYWIWFHYIS--------LLKYPYEAVLINEFDDPSRCFVKGVQ 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31121	NP_733058.1	P-loop_NTPase	319..518	CDD:304359	60/208 (29%)
		cbiO	319..491	CDD:130234	52/181 (29%)
		ABC2_membrane	621..809	CDD:279410	33/203 (16%)
ABCG18	NP_191071.1	3a01204	57..707	CDD:273361	124/570 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	80	1.000	Domainoid score	I2985
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920