DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31121 and ABCG20

DIOPT Version :9

Sequence 1:	NP_733058.1	Gene:	CG31121 / 42975	FlyBaseID:	FBgn0051121	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_190919.1	Gene:	ABCG20 / 824519	AraportID:	AT3G53510	Length:	739	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	134/560 - (23%)
Similarity:	250/560 - (44%)	Gaps:	72/560 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 LRGVSMQAKAGDLFAIMATSQREGSALAECLAG--LTERLGGEILINGQQVSRRGLRELCSYVPA 381
            |.|:|.:|:.|::.|::..|....|.|.:.||.  ..|.|.|:|.:||:.:.....:.:.:||
plant   127 LNGISGEAREGEMMAVLGASGSGKSTLIDALANRISKESLRGDITLNGEVLESSLHKVISAYV-- 189

  Fly   382 LEVSSLDPRMSVQCTLNFHAALRGP--IDRSDLEERMDVLIEDLGLNTVRASNVSTLTH-----S 439
            ::...|.|.::|:.||.|.|..|.|  :.:...:.|:..||:.|||.....:.:....|     .
plant   190 MQDDLLFPMLTVEETLMFSAEFRLPSSLSKKKKKARVQALIDQLGLRNAAKTVIGDEGHRGVSGG 254

  Fly   440 EKQRLSVACQLLAQSSLLILDQVTSNMDIFDTFFLVEYLRQWCSGGRIVIMTLQPPTFEILSMCS 504
            |::|:|:...::....:|.||:.||.:|....:.:|:.|::....|.||||::..|::.||.:..
plant   255 ERRRVSIGTDIIHDPIILFLDEPTSGLDSTSAYMVVKVLQRIAQSGSIVIMSIHQPSYRILGLLD 319

  Fly   505 GVLLLSGGRTVFSGSRADLPRHMGELGYPCPPFKNPADYYLDLV-TLDDLS-------------A 555
            .::.||.|.||:|||...||:...|.|:|.|..:|..::.|||: .|:|..             .
plant   320 KLIFLSRGNTVYSGSPTHLPQFFSEFGHPIPENENKPEFALDLIRELEDSPEGTKSLVEFHKQWR 384

  Fly   556 AAMLESSARIESLANAWDQIN---SEPPLAAPPASLPNF--TMKAGFFGQISALIKR--FAGYKQ 613
            |....|.:|..:..:..|.|:   |...|.:...:|.:.  |....|:.::..:.||  ....:|
plant   385 AKQTSSQSRRNTNVSLKDAISASISRGKLVSGATNLRSSFQTFANPFWTEMLVIGKRSILNSRRQ 449

  Fly   614 PGSLLTWISKLIAAAVLSLFIGCIFWDVPASDPQLSYHDRLGYHHCVMVLVYW------PLVMLT 672
            |.  |..| :|.|..|..:.:..|||.:..| |: ...:|||:....|...::      |:.:
plant   450 PE--LFGI-RLGAVLVTGMILATIFWKLDNS-PR-GIQERLGFFAFAMSTTFYTCAEAIPVFL-- 507

  Fly   673 IRDTQEDRRHAERDIRLGLYTRSLYIIVQSLLGLFPSLCIWLAYLLPAHSMAGLYTYSNSSDTGI 737
                 ::|....|:.....|.||.|::..:::.:...:.:..|:.....|..||   :..|:
plant   508 -----QERYIFMRETAYNAYRRSSYVLAHTIISIPALIILSAAFAASTFSAVGL---AGGSE--- 561

  Fly   738 YLYMGYMLLYLTLIQTLALFCA-----HLLPCKVSASIVNGLISLAVAA----VGGYLVHPQNLA 793
                |::..:.|:   |..|.|     ..|...||..::...:.:|:.|    ..|:.:....:.
plant   562 ----GFLFFFFTI---LTAFWAGSSFVTFLSGVVSHVMIGFTVVVAILAYFLLFSGFFISRDRIP 619

  Fly   794 QFWSWLQFVSPERWLLPVLVQDEYSAETLSNSAGLQLCRN 833
            .:|.|..::|..::....::|:|:...|.....|:|:..|
plant   620 LYWIWFHYLSLVKYPYEGVLQNEFEDPTKCFVRGIQMFDN 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31121	NP_733058.1	P-loop_NTPase	319..518	CDD:304359	59/207 (29%)
		cbiO	319..491	CDD:130234	50/180 (28%)
		ABC2_membrane	621..809	CDD:279410	39/202 (19%)
ABCG20	NP_190919.1	P-loop_NTPase	119..333	CDD:304359	59/207 (29%)
		3a01204	120..738	CDD:273361	134/560 (24%)
		ABC2_membrane	438..641	CDD:279410	44/227 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	80	1.000	Domainoid score	I2985
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920