DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31121 and ABCG21

DIOPT Version :9

Sequence 1:	NP_733058.1	Gene:	CG31121 / 42975	FlyBaseID:	FBgn0051121	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_001189973.1	Gene:	ABCG21 / 822149	AraportID:	AT3G25620	Length:	672	Species:	Arabidopsis thaliana

Alignment Length:	587	Identity:	146/587 - (24%)
Similarity:	253/587 - (43%)	Gaps:	110/587 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 RKQSGMGLIY-------PNIQVHCLDVNPCLRGVSMQAKAGDLFAIMATSQREGSALAECLAG-L 352
            :.|:|.|..:       ||..|        |:.||...|.|:|.|::..|....:.|...||| |
plant    78 KSQTGKGSYWFGSQEPKPNRLV--------LKCVSGIVKPGELLAMLGPSGSGKTTLVTALAGRL 134

  Fly   353 TERLGGEILINGQQVSRRGLRELCSYVPALEVSSLDPRMSVQCTLNFHAALRGP--IDRSDLEER 415
            ..:|.|.:..||:..: ..::....:|...:|  |.|.::|..||.:.|.||.|  :.|.:..|:
plant   135 QGKLSGTVSYNGEPFT-SSVKRKTGFVTQDDV--LYPHLTVMETLTYTALLRLPKELTRKEKLEQ 196

  Fly   416 MDVLIEDLGL-----NTVRASNVSTLTHSEKQRLSVACQLLAQSSLLILDQVTSNMDIFDTFFLV 475
            :::::.||||     :.:....:..::..|::|:|:..::|...|||:||:.||.:|......:|
plant   197 VEMVVSDLGLTRCCNSVIGGGLIRGISGGERKRVSIGQEMLVNPSLLLLDEPTSGLDSTTAARIV 261

  Fly   476 EYLRQWCSGGRIVIMTLQPPTFEILSMCSGVLLLSGGRTVFSGSRADLPRHMGELGY-PCPPFKN 539
            ..||....|||.|:.|:..|:..:..|...||:||.|..::||....:..:.|.:|| |...|.|
plant   262 ATLRSLARGGRTVVTTIHQPSSRLYRMFDKVLVLSEGCPIYSGDSGRVMEYFGSIGYQPGSSFVN 326

  Fly   540 PADYYLDLVT--LDDLSAAAMLESSARI----------ESLANAWDQINSEPPLAAP-----PAS 587
            |||:.|||..  ..|......:|::.|:          :||.:::.: |..|||...     |..
plant   327 PADFVLDLANGITSDTKQYDQIETNGRLDRLEEQNSVKQSLISSYKK-NLYPPLKEEVSRTFPQD 390

  Fly   588 LPNFTMK---------AGFFGQISALIKR---------FAGYKQPGSLLTWISKLIAAAVLSLFI 634
            ..|..::         ..::.|.|.|:||         |:|.           ::.....:||..
plant   391 QTNARLRKKAITNRWPTSWWMQFSVLLKRGLKERSHESFSGL-----------RIFMVMSVSLLS 444

  Fly   635 GCIFWDVPASDPQLSYHDRLGYHHCVMVLVYW---PLVMLTIRDTQEDRRHAERDIRLGLYTRSL 696
            |.::|....:..|    |::|.  .....::|   ||........|| |....::...|:|..|.
plant   445 GLLWWHSRVAHLQ----DQVGL--LFFFSIFWGFFPLFNAIFTFPQE-RPMLIKERSSGIYRLSS 502

  Fly   697 YIIVQS---------LLGLFPSLCIWLAYLLPAHSMAGLYTYSNSSDTGIYLYMGYMLLYLTLI- 751
            |.|.::         |..:|.::..|:..|.|            |..|.|...|  ::||..|:
plant   503 YYIARTVGDLPMELILPTIFVTITYWMGGLKP------------SLTTFIMTLM--IVLYNVLVA 553

  Fly   752 QTLALFCAHLLPCKVSASIVNGLISLAVAAVGGYLVHPQNLAQFWSWLQFVSPERWLLPVLVQDE 816
            |.:.|....:|.....|:.::.::.|.....|||.:  |::..|.:||::||...:...:||..:
plant   554 QGVGLALGAILMDAKKAATLSSVLMLVFLLAGGYYI--QHIPGFIAWLKYVSFSHYCYKLLVGVQ 616

  Fly   817 YS 818
            |:
plant   617 YT 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31121	NP_733058.1	P-loop_NTPase	319..518	CDD:304359	61/206 (30%)
		cbiO	319..491	CDD:130234	53/179 (30%)
		ABC2_membrane	621..809	CDD:279410	44/200 (22%)
ABCG21	NP_001189973.1	PLN03211	43..670	CDD:215634	146/587 (25%)
		P-loop_NTPase	89..304	CDD:304359	64/225 (28%)
		ABC2_membrane	416..615	CDD:279410	51/232 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820