DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31121 and NAP12

DIOPT Version :9

Sequence 1:	NP_733058.1	Gene:	CG31121 / 42975	FlyBaseID:	FBgn0051121	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_001323430.1	Gene:	NAP12 / 818275	AraportID:	AT2G37010	Length:	1082	Species:	Arabidopsis thaliana

Alignment Length:	756	Identity:	154/756 - (20%)
Similarity:	275/756 - (36%)	Gaps:	197/756 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 RQANSRASIAVGQHHHQMQQHQQQYGKHYGHRSHSEADLLGAGLSQVDGGGGGMGYDYNEARLYG 280
            |||.||.  |..:|..:..|.::::....|...:.:.. |.|.|||..........|....:..|
plant   325 RQAKSRE--AAARHAKETTQARERWKTAKGVAKNQKMG-LSAQLSQTFSRMKSARKDATPVKASG 386

  Fly   281 SSRQ------------------------YGNGNGHNPGSRKQSGMG------------------- 302
            .|:.                        :..|.|..||.:.|:..|
plant   387 KSKDKKKEPSNLTKMMKSMEENPSNNEGFNVGTGSKPGKKPQAPKGKQLHTQSQIFKYAYGQIEK 451

  Fly   303 ----------LIY---------------PNIQVHCLDVNPCLRG--------VSMQAKAGDLFAI 334
                      |.:               |.|:|...|:...|:|        |:.:...|.:.|:
plant   452 EKAMEQNNKNLTFSGVISMATDTEMRTRPVIEVAFKDLTLTLKGKHKHILRSVTGKIMPGRVSAV 516

  Fly   335 MATSQREG-------SALAECLAGLTERLGGEILINGQQVSRRGLRELCSYVPALEVSSLDPRMS 392
            |..|   |       ||||....|.|..  |.|||||:..|....:::..:||..:|  :...::
plant   517 MGPS---GAGKTTFLSALAGKATGCTRT--GLILINGRNDSINSYKKITGFVPQDDV--VHGNLT 574

  Fly   393 VQCTLNFHAALR--GPIDRSDLEERMDVLIEDLGLNTVRASNVST-----LTHSEKQRLSVACQL 450
            |:..|.|.|..|  ..:.::|....::.:||.|||..||.|.|.|     ::..:::|::|..::
plant   575 VEENLRFSARCRLSAYMSKADKVLIIERVIESLGLQHVRDSLVGTIEKRGISGGQRKRVNVGVEM 639

  Fly   451 LAQSSLLILDQVTSNMDIFDTFFLVEYLRQWCSGGRIVIMTLQPPTFEILSMCSGVLLLS-GGRT 514
            :.:.||||||:.|:.:|...:..|:..||:....|..:.|.:..|::.:..|...:::|: ||.|
plant   640 VMEPSLLILDEPTTGLDSASSQLLLRALRREALEGVNICMVVHQPSYTMYKMFDDMIILAKGGLT 704

  Fly   515 VFSGSRADLPRHMGELGYPCPPFKNPADYYLDL----------VTLDDLSAAAMLES-------- 561
            |:.||...:..:..::|...|...||.|:|:|:          :|::.|....||.:
plant   705 VYHGSVKKIEEYFADIGITVPDRVNPPDHYIDILEGIVKPDGDITIEQLPVRWMLHNGYPVPHDM 769

  Fly   562 -------------SARIESLANA-----WDQINSEPPLAAPPASLPNFTMKAGFFGQISALIKR- 607
                         ||:.:|..|:     |..:.:...:...... .|::.......:::..:.|
plant   770 LKFCDGLPSSSTGSAQEDSTHNSFSNDLWQDVKTNVEITKDQLQ-HNYSNSHDNSNRVTPTVGRQ 833

  Fly   608 ---FAGYKQPGSLLTWISKLIAAAVLSLFI--GCIFWDVPASDPQLSYHDRLGYHHCVMVLVYWP 667
               |.|  :.|......::|.|...|.|.:  .|:......:|..:   |.|||.:.: :.|...
plant   834 YRYFVG--RVGKQRLREARLQALDFLILLVAGACLGTLAKVNDETI---DTLGYTYTI-IAVSLL 892

  Fly   668 LVMLTIRDTQEDRRHAERDIRLGLYTRSLYIIVQSLLGLFPSLCIWLAYLLPAHSMAGLYTYSNS 732
            ..:..:|....|:....|:...|:.:                    ||:.:...:|..|.|....
plant   893 CKISALRSFSVDKLQYWRESAAGISS--------------------LAHFMAKDTMDHLNTIMKP 937

  Fly   733 SDTGIYLYMGYML---------LYLTLIQTLALFC----AHLLPCKVSASIVNGLISLAVAAVGG 784
            .   :||.|.|..         .|:.|:  ..::|    |::.....|.|... |:|:.|..|..
plant   938 L---VYLSMFYFFNNPRSSFEDNYIVLV--CLVYCVTGMAYIFAILYSPSAAQ-LLSVLVPVVMT 996

  Fly   785 YLVHPQNLAQFWSWLQFVSPERWLLPVLVQDEYSAETLSNS 825
            .:.:....:....:|......:|.|...|        |||:
plant   997 LIANQDKESMVLKYLGSFCYPKWTLEAFV--------LSNA 1029

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31121	NP_733058.1	P-loop_NTPase	319..518	CDD:304359	62/221 (28%)
		cbiO	319..491	CDD:130234	54/193 (28%)
		ABC2_membrane	621..809	CDD:279410	36/202 (18%)
NAP12	NP_001323430.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820