DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31121 and Abcg3

DIOPT Version :9

Sequence 1:	NP_733058.1	Gene:	CG31121 / 42975	FlyBaseID:	FBgn0051121	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	XP_038948191.1	Gene:	Abcg3 / 498327	RGDID:	1565568	Length:	703	Species:	Rattus norvegicus

Alignment Length:	602	Identity:	135/602 - (22%)
Similarity:	239/602 - (39%)	Gaps:	107/602 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 HNPGSRK--QSGMGLIYPNIQVHCLDVNPCLRGVSMQAKAGDLFAIMATSQREGSALAECLAGLT 353
            ||...|:  |||..|   ..|...::....:.|:    ....|.|||.......|.|.:.||...
  Rat    85 HNISYRETVQSGFPL---RQQTRVIERLSSISGI----MGPGLNAIMGPQDGSRSLLLDVLAARR 142

  Fly   354 E--RLGGEILINGQQVSRRGLRELCS--YVPALEVSSLDPRMSVQCTLNFHAALRGP--IDRSDL 412
            :  .|.|:||:||:.   |.....|:  |||..:|  :...::|:..|.|.||||.|  |.|.:.
  Rat   143 DPSGLSGDILVNGKP---RPANFKCTSGYVPQNDV--VMHTVTVRDNLEFSAALRLPMTITRDEK 202

  Fly   413 EERMDVLIEDLGLNTVRASNVSTLTHSEKQRLSVACQLLAQSSLLILDQVTSNMDIFDTFFLVEY 477
            ..|::.::|.|.|:  :..|....:...::|.|:|.:|:|:..:|.||..|:::|:..|.:::..
  Rat   203 RRRINEVLELLHLD--KEQNTKPRSKELRKRTSIAVELIAEHPILFLDDPTTDLDLTTTTYVISV 265

  Fly   478 LRQWCSGGRIVIMTLQPPTFEILSMCSGVLLLSGGRTVFSGSRADLPRHMGELGYPCPPFKNPAD 542
            ||:....|:.:|.::..|.:.|......:.|::.|:.:|.|...|...:....||......||||
  Rat   266 LRRMSMKGKTIIFSINQPQYSIFRFFDSLTLVASGKLMFHGPARDALEYFTSAGYQYESHNNPAD 330

  Fly   543 YYLDLV------TLDDLSAA-----------------AMLESSARIESLANA-WDQINSEPPLAA 583
            ::||::      |.:|...|                 |.:.:.:|:.|...| .||:..:..|
  Rat   331 FFLDVINGGLCDTEEDGHEAGNYEELFERKYQATKKLANMYAQSRLHSDTRARLDQLLGQQQL-- 393

  Fly   584 PPASLPNFTMKAGFFGQISALIKRFAGYKQ-PGSLLTWISKLIAAAVLSLFIGCIFWDVPASDPQ 647
            ...|....|....|:.|:..:  .:..:|. .|.||....:.:..|.|:..:|..|
  Rat   394 DRNSAVETTCVTPFWHQLMWI--TYQSFKNIRGFLLVTAKQAVITATLAALVGIAF--------- 447

  Fly   648 LSYHDRLGYHHCVMV-----LVYWPLVMLTIRDTQE------DRRHAERDIRLGLYTRSLYIIVQ 701
                 ::..:.|:.|     |:|...:...|.....      ||.....:...|.|..|.|...:
  Rat   448 -----QILKNGCIEVYIRAGLLYLLTIFQCITSVSAGELFVIDRDRFLHEHTSGYYRVSSYFFGK 507

  Fly   702 SLLGLFPSLCIWLAYLLPAHSMAGLYTYSNSSDTGIYLYMGYMLLYLTLIQTLALFCAHLLPCKV 766
            .|..|.|...:....:|..:.:||:.|..:|....::..|  ||.|          .|..||..:
  Rat   508 LLAELIPRRLLPSTIVLITYFIAGVKTSMSSFFAMLFTVM--MLAY----------SASSLPLSI 560

  Fly   767 SASIVNGLISLAVAAV------------GGYLVHPQNLAQFWSWLQFVSPERWLLPVLVQDEYSA 819
            .|    |..::||..:            .|..::..:|....||:|:.:...:....|:.:|:..
  Rat   561 GA----GENAVAVPTLFVTIYFVFMLFFSGLSLYSGSLLPQLSWIQYFNIPHYGFKALLHNEFLG 621

  Fly   820 ETLSNSAGLQ---LCRN 833
            :...:...::   .|.|
  Rat   622 QNFCSEHNIEEVSRCHN 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31121	NP_733058.1	P-loop_NTPase	319..518	CDD:304359	56/204 (27%)
		cbiO	319..491	CDD:130234	51/177 (29%)
		ABC2_membrane	621..809	CDD:279410	39/210 (19%)
Abcg3	XP_038948191.1	3a01204	109..683	CDD:273361	127/575 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010