Protein Alignment CG11089 and purH

DIOPT Version :10

• Sequence 1: NP_651305.1
• Gene: CG11089 / 42973
• FlyBaseID: FBgn0039241
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_418434.1
• Gene: purH / 948503
• ECOCYCID: EG10795
• Length: 529
• Species: Escherichia coli
• Alignment Length: 611
• Identity: 214/611 - (35%)
• Similarity: 303/611 - (49%)
• Gaps: 118/611 - (19%)

  Fly     7 ALLSVSDKTGLLDLGKSLVALGFDLVASGGTATSLRGAGLKVRDVSEITGAPEMLGGRVKTLHPA 71
            ||||||||.|:::..::|.|.|.:|:::||||..|...||.|.:||:.||.|||:.||||||||.
E. coli    10 ALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPK 74

  Fly    72 VHAGILSRTTDSDLADMRKQGFDLIQLVVCNLYPFASTVAKPDVTLADAVENIDIGGVTLLRAAA 136
            ||.|||.|....| |.|.:.....|.:||.||||||.|||:...:|.||||||||||.|::|:||
E. coli    75 VHGGILGRRGQDD-AIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAA 138

  Fly   137 KNHQRVTVVCEAVDYDRVLSELKAS-GNTTVETRQALALKAFTHTATYDDAISDYF--------- 191
            |||:.|.:|.::.|||.::.|:..: |:.|:.||..||:|||.|||.||..|::||
E. coli   139 KNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHG 203

  Fly   192 RKQYGSG----------VSQLPLRYGMNPHQKPAQLYTQLAKLPLTVLNASP------GFINLCD 240
            ..:..:|          :.:|.:|||.|.||: |..|.:......:|..|:.      .:.|:.|
E. coli   204 ESKEAAGRFPRTLNLNFIKKLDMRYGENSHQQ-AAFYIEENVKEASVATATQVQGKALSYNNIAD 267

  Fly   241 ALNGWQLVRELKKALQLPAATSFKHVSPAGAAVGVPLNPAQAKLCMVDDLYEQLTPLATAYARAR 305
            .....:.|:|..:    ||....||.:|.|.|:|                    ..:..||.||.
E. coli   268 TDAALECVKEFAE----PACVIVKHANPCGVAIG--------------------NSILDAYDRAY 308

  Fly   306 GADRMSSFGDFVALSDVCDVVTAR-IISREVSDGIIAAGYEPEALEILKKKKNGGYCILQMDPNY 369
            ..|..|:||..:|.:...|..||: ||||:..:.|||.....|||:|...|:|............
E. coli   309 KTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGER 373

  Fly   370 EPSAVERKTIFGLTLEQKRNDAVIDASLFSNVVSKRGPLPEVAVRDLIVATIALKYTQSNSVCYA 434
            .| .::.|.:.|..|.|.|:..::.|... .||:||.| .|..:||.:......|:.:||::.||
E. coli   374 VP-GLDFKRVNGGLLVQDRDLGMVGAEEL-RVVTKRQP-SEQELRDALFCWKVAKFVKSNAIVYA 435

  Fly   435 RDGQVVGIGAGQQSRIHCTRLAGEKADNWWLRQHPSVAGMKFKAGVKRAEISNAIDNYVNGTVGK 499
            ::...:||||||.||::..::||.||.:
E. coli   436 KNNMTIGIGAGQMSRVYSAKIAGIKAAD------------------------------------- 463

  Fly   500 DMPLSQFEGMFDKAPAQLTSEQKVEWLKQLSGVALGSDAFFPFRDNIDRASLSGVSYIASPAGST 564
                   ||:                  ::.|.::.|||||||||.||.|:.:||:.:..|.||.
E. coli   464 -------EGL------------------EVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSI 503

  Fly   565 NDAGVIAACDEHGIIMAHTNLRLFHH 590
            .|..||||.|||||.|..|::|.|.|
E. coli   504 RDDEVIAAADEHGIAMLFTDMRHFRH 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11089	NP_651305.1	IMPCH	5..191	CDD:238709	96/184 (52%)
		PRK07106	201..590	CDD:180841	114/395 (29%)
purH	NP_418434.1	purH	4..529	CDD:234854	213/609 (35%)