Protein Alignment CG11089 and ADE17

DIOPT Version :10

• Sequence 1: NP_651305.1
• Gene: CG11089 / 42973
• FlyBaseID: FBgn0039241
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_013839.1
• Gene: ADE17 / 855149
• SGDID: S000004727
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 589
• Identity: 363/589 - (61%)
• Similarity: 442/589 - (75%)
• Gaps: 3/589 - (0%)

  Fly     4 SKIALLSVSDKTGLLDLGKSLVALGFDLVASGGTATSLRGAGLKVRDVSEITGAPEMLGGRVKTL 68
            :|.|:|||.||||||||.:.|:.....::||||||..:|.||..:.|||.||.||||||||||||
Yeast     5 TKTAILSVYDKTGLLDLARGLIEKNVRILASGGTARMIRDAGFPIEDVSAITHAPEMLGGRVKTL 69

  Fly    69 HPAVHAGILSRTTDSDLADMRKQGFDLIQLVVCNLYPFASTVAKPDVTLADAVENIDIGGVTLLR 133
            |||||.|||:|..|||..|:::|..:.:..||||||||..||||..||:.:|||.||||||||||
Yeast    70 HPAVHGGILARDIDSDEKDLKEQHIEKVDYVVCNLYPFKETVAKVGVTIPEAVEEIDIGGVTLLR 134

  Fly   134 AAAKNHQRVTVVCEAVDYDRVLSELKASGNTTVETRQALALKAFTHTATYDDAISDYFRKQYGSG 198
            ||||||.|||::.:..||...||||.::|..:.:.|..||||||.|||.||.||||:|||||..|
Yeast   135 AAAKNHARVTILSDPKDYSEFLSELSSNGEISQDLRNRLALKAFEHTADYDAAISDFFRKQYSEG 199

  Fly   199 VSQLPLRYGMNPHQKPAQLY-TQLAKLPLTVLNASPGFINLCDALNGWQLVRELKKALQLPAATS 262
            .:|:.||||.||||||||.| :|...||..||..|||:|||.||||.|.||:||..:|.||||.|
Yeast   200 QAQITLRYGANPHQKPAQAYVSQQDSLPFKVLCGSPGYINLLDALNSWPLVKELSASLNLPAAAS 264

  Fly   263 FKHVSPAGAAVGVPLNPAQAKLCMVDDLYEQLTPLATAYARARGADRMSSFGDFVALSDVCDVVT 327
            ||||||||||||:||:..:.::..|.|: |.|:|||.||||||||||||||||::|||::.||.|
Yeast   265 FKHVSPAGAAVGIPLSDVEKQVYFVADI-ENLSPLACAYARARGADRMSSFGDWIALSNIVDVPT 328

  Fly   328 ARIISREVSDGIIAAGYEPEALEILKKKKNGGYCILQMDPNYEPSAVERKTIFGLTLEQKRNDAV 392
            |:|||||||||:||.|||||||.||.|||.|.|||||:||||.|.||||:.::|:|||||||||:
Yeast   329 AKIISREVSDGVIAPGYEPEALAILSKKKGGKYCILQIDPNYVPEAVERRQVYGVTLEQKRNDAI 393

  Fly   393 IDASLFSNVVSKRGPLPEVAVRDLIVATIALKYTQSNSVCYARDGQVVGIGAGQQSRIHCTRLAG 457
            |:.|.|..:||:...|.|.|:.||.|||||:||||||||||||:|.|||:|||||||||||||||
Yeast   394 INQSTFKEIVSQNKNLTEQAIIDLTVATIAIKYTQSNSVCYARNGMVVGLGAGQQSRIHCTRLAG 458

  Fly   458 EKADNWWLRQHPSVAGMKFKAGVKRAEISNAIDNYVNGTVGKDMP-LSQFEGMFDKAPAQLTSEQ 521
            :||||||.||||.|..:|:..||||.|.|||||.:|.|.:..:.| ||:::..|::.|...|.|:
Yeast   459 DKADNWWFRQHPRVLEIKWAKGVKRPEKSNAIDLFVTGQIPTEEPELSEYQSKFEEIPKPFTPEE 523

  Fly   522 KVEWLKQLSGVALGSDAFFPFRDNIDRASLSGVSYIASPAGSTNDAGVIAACDEHGIIMAHTNLR 586
            :.|||.:|:.|:|.|||||||.||:.||..|||.|||:|:||..|..|.:|.|...::.....:|
Yeast   524 RKEWLSKLTNVSLSSDAFFPFPDNVYRAVKSGVKYIAAPSGSVMDKVVFSAADSFDLVYVENPIR 588

  Fly   587 LFHH 590
            ||||
Yeast   589 LFHH 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11089	NP_651305.1	IMPCH	5..191	CDD:238709	113/185 (61%)
		PRK07106	201..590	CDD:180841	242/390 (62%)
ADE17	NP_013839.1	purH	6..546	CDD:273032	341/540 (63%)