Protein Alignment CG3744 and DAP2

DIOPT Version :10

• Sequence 1: NP_733056.3
• Gene: CG3744 / 42972
• FlyBaseID: FBgn0039240
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: NP_011893.1
• Gene: DAP2 / 856423
• SGDID: S000001070
• Length: 818
• Species: Saccharomyces cerevisiae
• Alignment Length: 722
• Identity: 190/722 - (26%)
• Similarity: 299/722 - (41%)
• Gaps: 166/722 - (22%)

  Fly   432 NSDMIAYISDCDLFVTHTLSGHEKRLTYTSTGRHSYVDDALSAGVPSYVMQEE-FSRYQGFWWQP 495
            ||:.|||:.|.::::...:|  :|.:...:....|:    |..|.|.:|.:|| |...:..||.|
Yeast   197 NSNDIAYVQDNNIYIYSAIS--KKTIRAVTNDGSSF----LFNGKPDWVYEEEVFEDDKAAWWSP 255

  Fly   496 HSNDGIYRIVYEEVDESEVSVYTFP----SSTAMHGRVDEYRFPRTGSPNAKSKLKLVQFVLNEA 556
               .|.| :.:.::|||||..:..|    ....::..:...::|::|:||
Yeast   256 ---TGDY-LAFLKIDESEVGEFIIPYYVQDEKDIYPEMRSIKYPKSGTPN--------------- 301

  Fly   557 LQVSEIAIKDLPYSLLAVFSWLE-----------------YIVRVGWTPDAKYVWVQGLDRKQQR 604
                       |::.|.|:|..:                 .|..|.|..:.. |.|:..||....
Yeast   302 -----------PHAELWVYSMKDGTSFHPRISGNKKDGSLLITEVTWVGNGN-VLVKTTDRSSDI 354

  Fly   605 LDVILIPLDNFCESYSSQVSTPTDSIGDHSWRSLYSRTITPLQVIYTERSDS--WINVHDMLHFL 667
            |.|.||                 |:|...|            .|:..|.|:.  |...|:.|
Yeast   355 LTVFLI-----------------DTIAKTS------------NVVRNESSNGGWWEITHNTL--- 387

  Fly   668 DLTETSVTFLWASEETGFRHLYLVTASLLLSQANGQPDPGSVGAQPSFVDLSALQPRILNKVA-- 730
                    |:.|:|.....|             ||..|...:|.              .|.:|
Yeast   388 --------FIPANETFDRPH-------------NGYVDILPIGG--------------YNHLAYF 417

  Fly   731 ----------LTSGEWEVLARNLWVDKANKLVYFVGLRDTPLEKHLYVVSLERPEHIRLLTEPGY 785
                      ||.|:|||:...|..|.....:||:..|.:..|:|:|.:.|..|..|..:|:...
Yeast   418 ENSNSSHYKTLTEGKWEVVNGPLAFDSMENRLYFISTRKSSTERHVYYIDLRSPNEIIEVTDTSE 482

  Fly   786 S--YLVEFDDQCKLMLLVYCNIQRLPSCKVM----RVNQTCSNGGVNGIQI-------SLVGYLH 837
            .  |.|.|....:..||.|.. .::|..|::    |..:.|..|.|.|..:       .|...|.
Yeast   483 DGVYDVSFSSGRRFGLLTYKG-PKVPYQKIVDFHSRKAEKCDKGNVLGKSLYHLEKNEVLTKILE 546

  Fly   838 EGGKPEPQYCP-QIFSPQLPSGDIVYAMVFKPHNFE--LGVKYPTVLNVYGGPEVQTVNNTFK-G 898
            :...|...:.. .:...:.....:|.:....|::|:  |...||.....||||..|.|..||. |
Yeast   547 DYAVPRKSFRELNLGKDEFGKDILVNSYEILPNDFDETLSDHYPVFFFAYGGPNSQQVVKTFSVG 611

  Fly   899 KHQLRMHMLAAQGYCVICIDSRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQLGYIDMDR 963
            .:::....|.|   .|:.:|.||:..:|:.|.|.:|.|:|..|..||:.| .||...|.::|..:
Yeast   612 FNEVVASQLNA---IVVVVDGRGTGFKGQDFRSLVRDRLGDYEARDQISA-ASLYGSLTFVDPQK 672

  Fly   964 VAIHGWSYGGYLSLMGLVQ-YPKIFKVAIAGAPVTNWEYYDTGYTERYMDMPQNNEAGYSAGSVL 1027
            :::.||||||||:|..|.: ..:.||..::.||||:|.:||:.||||||..||.|..||...||
Yeast   673 ISLFGWSYGGYLTLKTLEKDGGRHFKYGMSVAPVTDWRFYDSVYTERYMHTPQENFDGYVESSV- 736

  Fly  1028 EYVNSFPEEDKRLLLIHGLIDENVHFCHTSRLISALN-KANKPYEVHLFPEERHSLRNLESNKNY 1091
            ..|.:..:.: |.||:||..|:||||.::.:.:..|: ...:.|:||:||:..||:|...:|...
Yeast   737 HNVTALAQAN-RFLLMHGTGDDNVHFQNSLKFLDLLDLNGVENYDVHVFPDSDHSIRYHNANVIV 800

  Fly  1092 ETKLLSF 1098
            ..|||.:
Yeast   801 FDKLLDW 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3744	NP_733056.3	DPPIV_N	419..802	CDD:395744	88/407 (22%)
		Peptidase_S9	902..1101	CDD:459761	76/199 (38%)
DAP2	NP_011893.1	DPPIV_N	148..508	CDD:395744	89/415 (21%)
		Peptidase_S9	608..815	CDD:459761	78/206 (38%)