Protein Alignment CG3744 and ome

DIOPT Version :10

• Sequence 1: NP_733056.3
• Gene: CG3744 / 42972
• FlyBaseID: FBgn0039240
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: NP_001097606.1
• Gene: ome / 44297
• FlyBaseID: FBgn0259175
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 1210
• Identity: 262/1210 - (21%)
• Similarity: 427/1210 - (35%)
• Gaps: 376/1210 - (31%)

  Fly     2 ESRTQMNQSNQQQQQQRNRLPSSPS-------PPLSVVSLTGGPNANTTLMGLEHDAVPSSQLGR 59
            :.:.|:....||.||.:::|.:|.|       |.    ..|||.|....:.....|..|..|  .
  Fly    55 QQQRQLQWEQQQHQQLQHQLTNSSSEFDEFHWPS----KQTGGENLGGKIYITPADIPPPPQ--P 113

  Fly    60 NNNNGGGHHRSHSITNAATTSLANLLDGFTARVSTAVSVAGGTNMLMDRSSQSAASTPGSTHS-- 122
            .:.:|...|..|:                            |:|    |..|.....|.|.||
  Fly   114 PHQSGSNSHSHHN----------------------------GSN----RQQQQHQQHPHSLHSHI 146

  Fly   123 ----------------------IASLTSMGSLGTTANALYSSIGSALNSITSPIQAAAAAATATT 165
                                  ..|:..||         |.      :|:     .|.|.|:.|.
  Fly   147 HPHPHPHHQHGHRTPPHRCKCEHPSIELMG---------YE------DSV-----IATATASNTA 191

  Fly   166 TEVVVAAASVITNHLSSPTSGTPPHGLDVDEGDDECDDCEED--------EDDPVDNDGHIAAPT 222
            ..|.||....:..|..      ||:......|........|.        |||...:.|...
  Fly   192 ANVGVAGGGGVGRHQH------PPYYYKAAVGRRSSAKLHESMLGGGSSLEDDDGTSAGSFG--- 247

  Fly   223 PNKSWAENKQVVQEIRKKMCNLSSMVPTNVQFRHLSDGRARCYFLGTPPQSWETTLLFADINLTQ 287
            ...|..:|....:|.::::..:.::|.|.:....|:                 |.|:|    :.:
  Fly   248 EGMSRFKNLMHTKEKKRRVRIILTVVTTVIAVALLA-----------------TALVF----ILR 291

  Fly   288 SEEQQLLVQRLEGIASDEWSPTMNA--GSPTSSGHQPAFLFNSLPRPRLPWSPLLQQPIQSSGGS 350
            ::|:.         |.|..|.:.||  .....||...|..||                     ||
  Fly   292 TDEKD---------ADDSDSNSNNAIDLEDVLSGQLYAKRFN---------------------GS 326

  Fly   351 GGSGSASPYAREYQLLQ------ERKRLSTWGITSYELHKPS--GKLVFPCFN------------ 395
            ..:|::..|.....:::      ||..|.. ....|.|::.|  |:.:....|
  Fly   327 WSNGNSLIYKENTSIMEFDAKTGERSILLE-DAQHYVLYEKSADGEFLLLAKNYKKNFRYSFLAE 390

  Fly   396 -DLYQCLDTGYNSGLLFPTQLR--TCPQWTALDPQICPQNSDMIAYISDCDLFVTHTLSGHEKRL 457
             |||. |:|.....|....:..  :..||:.:.      |:.:|.|  |.:|:...:....|..|
  Fly   391 YDLYN-LNTKEFIQLTIQNEQHYLSMVQWSPVG------NALVINY--DRNLYYKESALAQEIAL 446

  Fly   458 TYTSTGRHSYVDDALSAGVPSYVMQEE-FSRYQGFWWQPHSNDGIYRIVYEEVDESEVSVYTFPS 521
            |       |.....:..|:|.:|.:|| ||.....|:.|...    ::.:.:.|:|...:..||
  Fly   447 T-------SDEQAGILNGIPDWVYEEEVFSSNVATWFNPSGT----QLAFIKFDDSSTHLINFP- 499

  Fly   522 STAMHGRVDEYR----------FPRTGSPNAKSKLKLVQFVLNEALQVSE-IAIKDLPYSLLAVF 575
               .:|...:.|          :|:.||.|.:.:|.:|.  |..|:...: :.:..:|   .|:.
  Fly   500 ---YYGDAGDLRYQYPLHQVIAYPKAGSSNPRVELVMVD--LKRAVAGGDFVTVMPVP---SALN 556

  Fly   576 SWLEYIVR-VGWTPDAKY--VWV------------QGLDRKQQRLDVILIPLDNFCESYSSQVST 625
            :..:|||. |.|..|...  :|:            .||:||     ||          ||::..|
  Fly   557 TETDYIVTVVSWVDDDNVLSIWMNRIQNAAYVVTFDGLNRK-----VI----------YSAESKT 606

  Fly   626 PTDSIGDHSWRSLYSRTITPLQVIYTERSDSWINVHDMLHFLDLTETSVTFLWASEETGFRHLYL 690
                    .|..||:..       :..|:.|                  ...:......::|:.|
  Fly   607 --------GWVDLYTAP-------FRNRNGS------------------RLAFVLPHNNYKHVQL 638

  Fly   691 VTASLLLSQANGQPDPGSVGAQPSFVDLSALQPRILNKVALTSGEWEVLARNLWVDKANKLVYFV 755
            :::::    |:.:|              .||:|       ||.|::.|.:...|..|.:.:.|..
  Fly   639 LSSTV----ASSEP--------------QALEP-------LTEGKYVVDSILHWDGKNDIIFYTA 678

  Fly   756 GLRDTPLEKHLYVVSLERPEHIRLLTEPGYSYLVEFDDQCKLMLLVYCNIQRLPSCKVMRVNQTC 820
            ...|.|.:.|||.:.....:..:.||                     ||:  :.|..|.:...:.
  Fly   679 NTEDHPEQLHLYAIRALAKQSPKCLT---------------------CNL--IKSGDVQQTYFSA 720

  Fly   821 SNGGVNGIQISLVG------YLHE--------------------------GGKPEPQYCPQIFSP 853
            :....|.|.|:.:|      :::|                          .|...|.:  :|.:.
  Fly   721 TFNDNNHIVITSLGPGIPTTHIYEWKYENSQVVISKVLDWETNESLRAKLKGVALPSH--KILTV 783

  Fly   854 QLPSGDIVYAMVFKPHNFEL--GVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHMLAAQGYCVIC 916
            .:..|.....::..|.|.:.  ..|||.:::|||||:..:|.|  |.......::.:.|......
  Fly   784 DIDGGFQAKVLLQLPPNLDTSGATKYPMLVDVYGGPDSYSVTN--KWMVDWGTYLSSNQSVIYAK 846

  Fly   917 IDSRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQLGYIDMDRVAIHGWSYGGYLSLMGLV 981
            ||.|||..||:.....|..::|.||::||::..:.||....|||.|.|.|.|||||||.:.|.|.
  Fly   847 IDGRGSGLRGESLLHAIYLKLGTVEISDQINVTQKLSTLFNYIDPDHVGIWGWSYGGYAAAMALA 911

  Fly   982 -QYPKIFKVAIAGAPVTNWEYYDTGYTERYMDMPQNNEAGYSAGSVLEYVNSFPEEDKRLLLIHG 1045
             ...|:||.|.:.||||:|.|||:.||||||.:|..||.|| |.|.|..: :.....|:.||:||
  Fly   912 NDEAKVFKCAASIAPVTDWAYYDSIYTERYMGLPNTNELGY-ANSRLSTM-AVKLRGKKYLLVHG 974

  Fly  1046 LIDENVHFCHTSRLISALNKANKPYEVHLFPEERHSLRNL 1085
            .:|:|||:.....|...|.:.:..::...:.:|.|.|.|:
  Fly   975 TLDDNVHYQQAMILAKNLERQDILFKQISYADEDHGLSNV 1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3744	NP_733056.3	DPPIV_N	419..802	CDD:395744	78/409 (19%)
		Peptidase_S9	902..1101	CDD:459761	72/185 (39%)
ome	NP_001097606.1	DPPIV_N	367..739	CDD:395744	95/496 (19%)
		Peptidase_S9	828..1033	CDD:459761	72/189 (38%)