Protein Alignment CG3744 and Dpp9

DIOPT Version :10

• Sequence 1: NP_733056.3
• Gene: CG3744 / 42972
• FlyBaseID: FBgn0039240
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: XP_217309.6
• Gene: Dpp9 / 301130
• RGDID: 1588575
• Length: 921
• Species: Rattus norvegicus
• Alignment Length: 908
• Identity: 357/908 - (39%)
• Similarity: 497/908 - (54%)
• Gaps: 110/908 - (12%)

  Fly   226 SWAENKQVVQEIRKKMCNLSSMVPTNVQFRHLSDGRA----RCYFLGTPPQSWETTLLFADINLT 286
            ||...:.::...||....:.|..|.:.||....|...    |.|:||.|..|.|.:||:::|...
  Rat    88 SWDGLRNIIHGSRKSSGLIVSKAPHDFQFVQKPDESGPHSHRLYYLGMPYGSRENSLLYSEIPKK 152

  Fly   287 QSEEQQLLVQRLEGIASDEWSPTMNAGSPTSSGHQPAFLFNSLPRPRLPWSPLLQQPIQSSGGSG 351
            ..:|..||                                       |.|..:|.. .|::...|
  Rat   153 VRKEALLL---------------------------------------LSWKQMLDH-FQATPHHG 177

  Fly   352 GSGSASPYAREYQLLQERKRLSTWGITSYELHKPSGKLVFPCFNDLYQCLDTGYNSGL---LFPT 413
                  .|:||.:||:|||||..:|||||:.|..||..:|...|.|:.|.|.|.|..:   :.|.
  Rat   178 ------VYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPL 236

  Fly   414 QLRTCPQWTALDPQICPQNSDMIAYISDCDLFVTHTLSGHEKRLTYTSTGRHSYVDDALSAGVPS 478
            :::|......:||:|||.:....::|::.||:|.:..:|.|:|||:...|..|.:|:..||||.:
  Rat   237 EIKTQCSGPRMDPKICPADPAFFSFINNNDLWVANIETGEERRLTFCHQGSASVLDNPKSAGVAT 301

  Fly   479 YVMQEEFSRYQGFWWQP----HSNDGI--YRIVYEEVDESEVSVYTFPSSTAMHGRVDEYRFPRT 537
            :|:||||.|:.|.||.|    ..:.|:  .||:|||||||||.|...||......:.|.||:|||
  Rat   302 FVIQEEFDRFTGCWWCPTASWEGSGGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRT 366

  Fly   538 GSPNAKSKLKLVQFVLNEALQVSEIAIKDLPYSLLAVFSWLEYIVRVGWTPDAKYVWVQGLDRKQ 602
            ||.|.|..|||.:...:...::.....|:|.....::|..:|||.|.|||.|.:|.|...|||.|
  Rat   367 GSKNPKIALKLAELQTDHQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGRYAWAMFLDRPQ 431

  Fly   603 QRLDVILIPLDNFCESYSSQVSTPTDSIGDHSWRS---LYSRTITPLQVIYTERSDSWINVHDML 664
            |||.::|:|...|..:..|:.          .|:.   ...:.:.|. :||.|.::.||||||:.
  Rat   432 QRLQLVLLPPALFIPTLESEA----------QWQEAARAIPKNVQPF-IIYEEVTNVWINVHDIF 485

  Fly   665 HFLDLTE--TSVTFLWASE-ETGFRHLYLVTASLLLSQANGQPDPGSVGAQPSFVDLSALQPRIL 726
            |.....|  ....||.|:| :|||.|||.||..|..:..: ..:|.| .|:..|      :..|.
  Rat   486 HPFPQAEGQQDFCFLRANECKTGFCHLYRVTVDLKTNDYD-WTEPLS-PAEDEF------KCPIK 542

  Fly   727 NKVALTSGEWEVLARN---LWVDKANKLVYFVGLRDTPLEKHLYVVSLERPEHIRLLTEPGYSYL 788
            .:|||||||||||:|:   :||::..|||||.|.:|||||.||||||.|....|..||.||:|:.
  Rat   543 EEVALTSGEWEVLSRHGSKIWVNEQTKLVYFQGTKDTPLEHHLYVVSYESAGEIVRLTTPGFSHS 607

  Fly   789 VEFDDQCKLMLLVYCNIQRLPSCKVMRVNQTCSNGGVNGIQISLVGYLH----------EGGKPE 843
            ........:.:..|.::...|...|.:::....:.            ||          |.....
  Rat   608 CSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDP------------LHKQPRFWASMMEAASCP 660

  Fly   844 PQYC-PQIFSPQLPSGDIVYAMVFKPHNFELGVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHML 907
            |.|. |:||.....:...:|.|::|||..:.|.|:||||.|||||:||.|||:|||...||::.|
  Rat   661 PDYVPPEIFHFHTRADVQLYGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTL 725

  Fly   908 AAQGYCVICIDSRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQLGYIDMDRVAIHGWSYG 972
            |:.||.|:.||.|||..||..||..::.:|||||:.|||:.|:.::::.|:||:.||||||||||
  Rat   726 ASLGYAVVVIDGRGSCQRGLHFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSRVAIHGWSYG 790

  Fly   973 GYLSLMGLVQYPKIFKVAIAGAPVTNWEYYDTGYTERYMDMPQNNEAGYSAGSVLEYVNSFPEED 1037
            |:||||||:..|::|||||||||||.|..|||||||||||:|:||:.||.||||..:|...|.|.
  Rat   791 GFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVEKLPNEP 855

  Fly  1038 KRLLLIHGLIDENVHFCHTSRLISALNKANKPYEVHLFPEERHSLRNLESNKNYETKLLSFLQ 1100
            .|||::||.:||||||.||:.|:|.|.:|.|||::.::|.||||:|..||.::||..||.|||
  Rat   856 NRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCRESGEHYEVTLLHFLQ 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3744	NP_733056.3	DPPIV_N	419..802	CDD:395744	152/397 (38%)
		Peptidase_S9	902..1101	CDD:459761	116/199 (58%)
Dpp9	XP_217309.6	Dpp_8_9_N	<82..193	CDD:466112	36/150 (24%)
		DPPIV_N	204..628	CDD:395744	164/442 (37%)
		Peptidase_S9	720..921	CDD:459761	116/199 (58%)