Protein Alignment CG3744 and Dpp6

DIOPT Version :9

• Sequence 1: NP_001262935.1
• Gene: CG3744 / 42972
• FlyBaseID: FBgn0039240
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: XP_038963130.1
• Gene: Dpp6 / 29272
• RGDID: 68402
• Length: 867
• Species: Rattus norvegicus
• Alignment Length: 1073
• Identity: 224/1073 - (20%)
• Similarity: 417/1073 - (38%)
• Gaps: 284/1073 - (26%)

  Fly    81 LANLLDGFTARVSTAVSVAGGTNMLMDRSSQSAASTPGSTHSIASLTSMGSLGTTANALYSSIGS 145
            :|:|...||.:::|               |:|..:.|.::|      .:|..|...:|....:|.
  Rat     1 MASLYQRFTGKINT---------------SRSFPAPPEASH------LLGGQGPEEDAGSKPLGP 44

  Fly   146 ALNSITSPIQAAAAAATATTTEVVVAAASVITNHLSSPTSGTPPHGLDVDEGDDECDDCEEDEDD 210
            ...:: :|.:...|                         .|.|....   :...:||:.::::|.
  Rat    45 QAQAV-APRERGGA-------------------------GGRPRFQY---QARSDCDEEDKNQDT 80

  Fly   211 PVDNDGHIAAPTPNKSWAENKQVVQEIRKKMCNLSSMVPTNVQFRHLSDGRARCYFLGTPPQSWE 275
            |::.  .:.:..|.::| :...:...:...:|   |::.|:|             .|.||.:
  Rat    81 PLEE--LVGSNPPQRNW-KGIAIALLVILVIC---SLIVTSV-------------ILLTPAE--- 123

  Fly   276 TTLLFADINLTQSEEQQLLVQRLEGIASDEWSPTMNAGSPTSSGHQP--------AFLFNSLPRP 332
                  |.:|:|.::     ..:|.:.|:::..           |.|        .|::    |.
  Rat   124 ------DTSLSQKKK-----VTVEDLFSEDFKI-----------HDPEAKWISDKEFIY----RE 162

  Fly   333 RLPWSPLLQQPIQSSGGSGGSGSASPYAREYQLLQERKRLSTWGITSYELHKPSGKLVFPCFN-- 395
            |.  ..::.:.::::..:              :|.|.|::.:.....||: .|..:.....:|
  Rat   163 RK--GSVILRNVETNNST--------------VLIEGKKIESLRAIRYEI-SPDKEYALFSYNVE 210

  Fly   396 DLYQCLDTGYNSGLLFPTQLRTCPQWTALDPQIC-----------PQNSDMIAYISDCDLFVTHT 449
            .:||...|||......|   ...||  :|||...           |:...:|....:...:..|.
  Rat   211 PVYQHSHTGYYVLSKIP---HGDPQ--SLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHV 270

  Fly   450 LSGHEKRLTYTSTGRHSYVDDALSAGVPSYVMQEEFSR-YQGFWWQPHSNDGIYRIVYEEVDESE 513
               .::.:...|||:...:.:.||    .::.:||..: :...||.|   ||. |:.|..:::|.
  Rat   271 ---GKQAIRVVSTGKEGVIYNGLS----DWLYEEEILKSHIAHWWSP---DGT-RLAYATINDSR 324

  Fly   514 VSVYTFPSST-AMHGRVDEYRFPRTGSPNAKSKLKLVQFVLNEALQVSEIAIKDLP----YSLLA 573
            |.:...|:.| :::..|..|.:|:.||.|....|.::.  ||......|:...|.|    |
  Rat   325 VPLMELPTYTGSVYPTVKPYHYPKAGSENPSISLHVIG--LNGPTHDLEMMPPDDPRMREY---- 383

  Fly   574 VFSWLEYIVRVGWTPDAKYVWVQGLDRKQQRLDVILIPLDNFCESYSSQVSTPTDSIGDHSWRSL 638
                  ||..|.|....| |.|..|:|.|   :|.::.|   |:: ::.|.|..
  Rat   384 ------YITMVKWATSTK-VAVTWLNRAQ---NVSILTL---CDA-TTGVCTKK----------- 423

  Fly   639 YSRTITPLQVIYTERSDSWINVHDMLHFLDLTETSVTFLWASEETGFRHLYLVTASLLLSQANGQ 703
                       :.:.|::|::..:.............|:.|..:.|....|.:|.|  .||.|..
  Rat   424 -----------HEDESEAWLHRQNEEPVFSKDGRKFFFVRAIPQGGRGKFYHITVS--SSQPNSS 475

  Fly   704 PDPGSVGAQPSFVDLSALQPRILNKVALTSGEWEVLARNLWVDKANKLVYFVGLRDTPLEKHLY- 767
            .|                     |..::|||:|:|.....:.:|.||| ||:...|.|..:|||
  Rat   476 ND---------------------NIQSITSGDWDVTEILTYDEKRNKL-YFLSTEDLPRRRHLYS 518

  Fly   768 ----------VVSLERPEHIRLLTEPGYSYLVEFDDQCKLMLLVYCNIQRLPSCKV--------- 813
                      .:|.:..|:...:: ..:|:.::|       .|:.|....:|:..|
  Rat   519 ANTVDDFNRQCLSCDLVENCTYVS-ASFSHNMDF-------FLLKCEGPGVPTVTVHNTTDKRRM 575

  Fly   814 --MRVNQTCSNGGVNGIQISLVGYLHEGGKPEPQYCP-QIFSPQLPSGDIVYAMVFKPHNFELGV 875
              :..|:.... .:|..|:           |:.:|.. ::....||      ..:.||..|....
  Rat   576 FDLEANEQVQK-AINDRQM-----------PKIEYRKIEVEDYSLP------MQILKPATFTDTA 622

  Fly   876 KYPTVLNVYGGPEVQTVNNTFKGKHQLRMHMLAAQGYCVICIDSRGSRHRGKRFESHIRGRMGQV 940
            .||.:|.|.|.|..|:|:..|:...:  ..::::.|..|:..|.|||..:|.:....:|.|:|.:
  Rat   623 HYPLLLVVDGTPGSQSVSERFEVTWE--TVLVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGFL 685

  Fly   941 ELTDQVDALRS-LSDQLGYIDMDRVAIHGWSYGGYLSLMGL----VQYPKIFKVAIAGAPVTNWE 1000
            |..||::|:|: |.:|  |||..|||:.|..||||||...|    ....:.|....|.:|:|:::
  Rat   686 EEKDQMEAVRTMLKEQ--YIDKTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFK 748

  Fly  1001 YYDTGYTERYMDMPQNNEAGYSAGSVLEYVNSFPEEDKRLLLIHGLIDENVHFCHTSRLISALNK 1065
            .|.:.::|||:.:...:...|....:...|::.  ||::.|:||...||.:||.||:.||:.|.|
  Rat   749 LYASAFSERYLGLHGLDNRAYEMTKLAHRVSAL--EDQQFLIIHATADEKIHFQHTAELITQLIK 811

  Fly  1066 ANKPYEVHLFPEERHSLRNLESNKNYETKLLSF 1098
            ....|.:.::|:|.|...::...::....::.|
  Rat   812 GKANYSLQIYPDESHYFHSVALKQHLYRSIIGF 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3744	NP_001262935.1	DPPIV_N	419..802	CDD:279298	88/410 (21%)
		DAP2	<838..1099	CDD:224423	77/267 (29%)
		Peptidase_S9	902..1101	CDD:278741	61/202 (30%)
Dpp6	XP_038963130.1	DPPIV_N	197..563	CDD:395744	97/455 (21%)
		Abhydrolase	643..852	CDD:419691	62/208 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335168
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840