Protein Alignment CG3744 and dpf-3

DIOPT Version :10

• Sequence 1: NP_733056.3
• Gene: CG3744 / 42972
• FlyBaseID: FBgn0039240
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: NP_491956.1
• Gene: dpf-3 / 172409
• WormBaseID: WBGene00001056
• Length: 931
• Species: Caenorhabditis elegans
• Alignment Length: 963
• Identity: 262/963 - (27%)
• Similarity: 424/963 - (44%)
• Gaps: 236/963 - (24%)

  Fly   272 QSWE------TTLLFADINLTQSEEQQLLVQRLEGIASDEWSPTMNAGSPTSSGHQPAFLFN-SL 329
            :||:      ||..|..|:|.::|:.:|.:..:..:          .|:.|.|      :|: ::
 Worm    53 RSWKTEVRGMTTQGFTKISLMRAEKDRLNMYAISSV----------PGTNTQS------IFSVTI 101

  Fly   330 PRPRLPWSPLLQQPIQSSGGSG--------GSGSASPYAREYQLLQERKRLS-TWGITSYELHKP 385
            |...:..:.:..:..:....||        .|...:|.:.|:.|..||:|.. ..||:.||:.
 Worm   102 PLELVEKAQVADRKFELKLKSGYNVDSYIRMSCRKTPPSAEFTLQCERQRSQVVTGISDYEIR-- 164

  Fly   386 SGKLVFPC------FNDLYQCL--------------------DTGYNSGLLFPTQLRTC----PQ 420
            :||::...      :|.|.:.|                    :....||      .:.|    ||
 Worm   165 NGKMILMAGDQLFRYNPLNEALAAIPIAVPDDQSSTEPMDISEGSITSG------TKGCSNEAPQ 223

  Fly   421 WTALDP-----------------------------QICPQNSDMIAYISDCDLF------VTHTL 450
            .:.:.|                             ::||.:|.::||:.:..::      :.|..
 Worm   224 SSTVPPVTRIPIKKPTTSTEKPATAPPTNNFVSSAKVCPADSSLLAYVLNKQVYIEKNGKIIHRT 288

  Fly   451 SGHEKRLTYTSTGRHSYVDDALSAGVPSYVMQEEFSRYQGFWWQPHSNDGIYRIVYEEVDESEVS 515
            |.:.|.:|               .|||||::|||..|::|.||    ::...|::||.|:|.:|:
 Worm   289 SSNSKHIT---------------NGVPSYIVQEELERFEGIWW----SESKTRLLYEHVNEEKVA 334

  Fly   516 VYTFPSSTAMHG--RVDEYRFPRTGSPNAKSKLKLVQFVLNEALQV---SEIAIKDLPYSLLAVF 575
                .|...::|  .|...::||.|:.||.|.|::|.....:|..|   .|:..|..|:
 Worm   335 ----ESQFGVNGDPPVAPMKYPRAGTKNAYSTLRMVILENGKAYDVPLKDEVIYKHCPF------ 389

  Fly   576 SWLEYIVRVGWTPDAKYVWVQGLDRKQQRLDVILIPLDNF---------CESYSSQVSTPTDSIG 631
              .|||.|.|:..|...||||.:.|.|.:..::|||..:|         .:..:.|:||.. ::|
 Worm   390 --YEYITRAGFFSDGTTVWVQVMSRDQAQCSLLLIPYTDFLLPEELGGSIKEDNLQLSTDL-NMG 451

  Fly   632 ---DHSWRSLYSR--------TITPLQVIYTERSDSWINVHDMLHFLDLTETS---VTFLWASEE 682
               |.|......:        |:.    |:..|:|.|||.|:.::.|.:|:..   ..|::..|:
 Worm   452 VWDDKSHEETMEKPPRGKLRGTVQ----IHKARNDYWINTHNAIYPLKITDEEHPMYEFIYCLEK 512

  Fly   683 TGFRHLYLVTASLLLSQANGQPDPGSVGAQPSFVDLSALQPRILNKVALTSGEWEVLARNLWVDK 747
            .....|.|::|.|   ..||.       .:.:...|...:...:||           :..:.||:
 Worm   513 PNGSCLALISAEL---DQNGY-------CRHTEEKLLMAENFSINK-----------SMGIVVDE 556

  Fly   748 ANKLVYFVGLRDTPLEKHLYVVSLERPEHIRLLTEPG----------------------YSYLVE 790
            ..:|||:|.....|.|.::.|......:|.: |||.|                      |...|.
 Worm   557 VRELVYYVANESHPTEWNICVSHYRTGQHAQ-LTESGICFKSERANGKLALDLDHGFACYMTSVG 620

  Fly   791 FDDQCKLMLLVYCNIQRLPSCKVMRVNQTCSNGGVNGIQISLVGYLHEGGKPEPQY-CPQIFSPQ 854
            ...:|:.....:...:.||| .|...|.|.|.               ..|:|:..: .|::...|
 Worm   621 SPAECRFYSFRWKENEVLPS-TVYAANITVSG---------------HPGQPDLHFDSPEMIEFQ 669

  Fly   855 -LPSGDIVYAMVFKPHNFELGVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHMLAAQGYCVICID 918
             ..:|.:.|||:.:|.||:...|||....|||||.:|.|:|.|.....:|...|   ||.|:.||
 Worm   670 SKKTGLMHYAMILRPSNFDPYKKYPVFHYVYGGPGIQIVHNDFSWIQYIRFCRL---GYVVVFID 731

  Fly   919 SRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQL-GYIDMDRVAIHGWSYGGYLSLMGLVQ 982
            :|||.|||..||.||..:||.||:.|||:.|:.|:::. |::||.||.:||||||||::|..:.:
 Worm   732 NRGSAHRGIEFERHIHKKMGTVEVEDQVEGLQMLAERTGGFMDMSRVVVHGWSYGGYMALQMIAK 796

  Fly   983 YPKIFKVAIAGAPVTNWEYYDTGYTERYMDMPQNNEAGYSAGSVLEYVNSFPEEDKRLLLIHGLI 1047
            :|.|::.||||..|::|..|||.||||||..|. .|..|.|.|:...|...|:|..||:|:|||:
 Worm   797 HPNIYRAAIAGGAVSDWRLYDTAYTERYMGYPL-EEHVYGASSITGLVEKLPDEPNRLMLVHGLM 860

  Fly  1048 DENVHFCHTSRLISALNKANKPYEVHLFPEERHSLRNLESNKNYETKLLSFLQ 1100
            ||||||.|.:.|:....|..|.:|:.:||.|||.:||.:::...:.:::.|.|
 Worm   861 DENVHFAHLTHLVDECIKKGKWHELVIFPNERHGVRNNDASIYLDARMMYFAQ 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3744	NP_733056.3	DPPIV_N	419..802	CDD:395744	106/467 (23%)
		Peptidase_S9	902..1101	CDD:459761	91/200 (46%)
dpf-3	NP_491956.1	DPPIV_N	249..578	CDD:395744	94/385 (24%)
		Peptidase_S9	710..918	CDD:459761	93/208 (45%)