Protein Alignment CG3744 and dpp8

DIOPT Version :10

• Sequence 1: NP_733056.3
• Gene: CG3744 / 42972
• FlyBaseID: FBgn0039240
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: XP_012813879.2
• Gene: dpp8 / 100124922
• XenbaseID: XB-GENE-991409
• Length: 893
• Species: Xenopus tropicalis
• Alignment Length: 973
• Identity: 371/973 - (38%)
• Similarity: 519/973 - (53%)
• Gaps: 136/973 - (13%)

  Fly   160 AATATTTEVVVAAASVITNHLSSPTSGTPPHGLDVDEGDDECDDCEEDEDDPVDNDGHIAAPTPN 224
            ||...|.:|.|.......:|.||.:||..|                  :.:|...:.|
 Frog     7 AAAMETEQVGVEIFESARSHGSSESSGGDP------------------KPEPFFVERH------- 46

  Fly   225 KSWAENKQVVQEIRKKMCNLSSMVPTNVQFRHLSDGRA----RCYFLGTPPQSWETTLLFADINL 285
             ||::.::::.:.||....:.:..|.:..|...:|..:    |.|:|....::.|.||.:::|
 Frog    47 -SWSQMRKLLADTRKYHGYMMAKAPHSFTFVKRNDPESPHSDRMYYLAMSGENRENTLFYSEI-- 108

  Fly   286 TQSEEQQLLVQRLEGIASDEWSPTMNAGSPTSSGHQPAFLFNSLPRPRLPWSPLLQQPIQSSGGS 350
                                 ...:|.|         |.|.       |.|.|||.
 Frog   109 ---------------------PKNINRG---------AVLM-------LSWKPLLD--------- 127

  Fly   351 GGSGSASP----YAREYQLLQERKRLSTWGITSYELHKPSGKLVFPCFNDLYQCLD---TGYNSG 408
              :..|:|    |:||.:||:||||:.|.||::::.|..||..:|...:.:|...|   .|:...
 Frog   128 --TFQATPDYGMYSREEELLRERKRIGTVGISAFDYHAESGTFLFQAGSAIYTVRDGGSRGFTKQ 190

  Fly   409 LLFPTQLRT-CPQWTALDPQICPQNSDMIAYISDCDLFVTHTLSGHEKRLTYTSTGRHSYVDDAL 472
            .|.|..|.| ||. ..:||.|||.:...:|::...||::.:..:|.|:|||:.........:||.
 Frog   191 PLQPQLLETSCPN-IRMDPTICPGDPSWMAFVHSNDLWIGNVETGEERRLTFVHKDLAGVEEDAH 254

  Fly   473 SAGVPSYVMQEEFSRYQGFWWQPH-----SNDGIYRIVYEEVDESEVSVYTFPSSTAMHGRVDEY 532
            ||||.::|:||||.||.|:||.||     |...|.||:|||.|||||.:....|......|.|.:
 Frog   255 SAGVATFVLQEEFDRYTGYWWCPHNEKTASGGQILRILYEENDESEVEIIHVTSPMLETRRTDSF 319

  Fly   533 RFPRTGSPNAKSKLKLVQFVLNEALQVSEIAIKDLPYSLLAVFSWLEYIVRVGWTPDAKYVWVQG 597
            |:|:.|:.|.|...||.:.:::...::.::..|:|......:|...|||.|.|||||.||.|...
 Frog   320 RYPKAGTANPKVTFKLSEIIVDAEGRILDVLDKELRQPFEIMFGGTEYIARAGWTPDGKYAWAIL 384

  Fly   598 LDRKQQRLDVILIPLDNF---------CESYSSQVSTPTDSIGDHSWRSLYSRTITPLQVIYTER 653
            |||.|.||.::|||...|         |...|   ::|:||             :||| |||.|.
 Frog   385 LDRLQTRLQIVLIPPALFVCPHKDPPECHWIS---NSPSDS-------------VTPL-VIYEET 432

  Fly   654 SDSWINVHDMLHFLDLT-ETSVTFLWASE-ETGFRHLYLVTASLLLSQANGQPDPGSVGAQPSFV 716
            :|.|||:||:|||...| :..:.||:||| :|||||||.:| |:|.:..|.:.....:|
 Frog   433 TDIWINIHDILHFFPQTRDDEIQFLFASECKTGFRHLYRIT-SMLRTGGNSKGSADLLG------ 490

  Fly   717 DLSALQPRILNKVALTSGEWEVLARN---LWVDKANKLVYFVGLRDTPLEKHLYVVSLERPEHIR 778
             |:..:..|..:||:||||||||.|:   :.||:.||||||.|.:|||||.||||.:.|.|..:.
 Frog   491 -LTDFRCHIKEEVAVTSGEWEVLGRHGSTIRVDEVNKLVYFEGTKDTPLEHHLYVANYETPGEVT 554

  Fly   779 LLTEPGYSYLVEFDDQCKLMLLVYCNIQRLPSCKVMRVNQTCSNGGVNGIQISLVGYLHEGGKPE 843
            .||:.|:|:.......|.:.:..|.: |.||. .|...:.|.|..............|.|.....
 Frog   555 RLTDLGFSHACCVSQHCDMFISRYSS-QTLPH-SVHLFHLTGSGSDPTQKDKEFWATLLESPGTL 617

  Fly   844 PQY-CPQIFSPQLPSGDIVYAMVFKPHNFELGVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHML 907
            |.| .|:|||....:|..:|.|:::||..:.|.||||||.:||||:||.|||.|||....|::.|
 Frog   618 PGYIAPEIFSFPSRTGFTLYGMMYRPHQLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTL 682

  Fly   908 AAQGYCVICIDSRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQLGYIDMDRVAIHGWSYG 972
            |:.||.|:.||:|||.|||.:||...:.:|||||:.|||:.|:.|:.:..:||:|||.:||||||
 Frog   683 ASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQVEIDDQVEGLQYLAAKHSFIDLDRVGVHGWSYG 747

  Fly   973 GYLSLMGLVQYPKIFKVAIAGAPVTNWEYYDTGYTERYMDMPQNNEAGYSAGSVLEYVNSFPEED 1037
            ||||||.|:|.|.||:|||||||||.|.:||||||||||..|..||.||..|||......||.|.
 Frog   748 GYLSLMALIQRPDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEHGYYLGSVAMQAEKFPSEP 812

  Fly  1038 KRLLLIHGLIDENVHFCHTSRLISALNKANKPYEVHLFPEERHSLRNLESNKNYETKLLSFLQ 1100
            .||||:||.:||||||.|||.|:|.|.::.|||::.::|:||||:|..||.::||..||.:||
 Frog   813 NRLLLLHGFLDENVHFAHTSILLSFLVRSGKPYDLQIYPQERHSIRVPESGEHYELHLLYYLQ 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3744	NP_733056.3	DPPIV_N	419..802	CDD:395744	156/401 (39%)
		Peptidase_S9	902..1101	CDD:459761	114/199 (57%)
dpp8	XP_012813879.2	Dpp_8_9_N	4..152	CDD:466112	47/220 (21%)
		DPPIV_N	165..585	CDD:395744	170/446 (38%)
		Peptidase_S9	677..881	CDD:459761	114/199 (57%)