DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB3 and CCNQ

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_689487.2	Gene:	CCNQ / 92002	HGNCID:	28434	Length:	248	Species:	Homo sapiens

Alignment Length:	225	Identity:	46/225 - (20%)
Similarity:	86/225 - (38%)	Gaps:	56/225 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 FQVSHYAMDIFNYLKVREAEFPIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKI 364
            |:|:.:.|:....|.:|  ..|||.       ..|.......:..::..:.:.:...::|||.|:
Human    28 FRVARFIMEAGVKLGMR--SIPIAT-------ACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKV 83

  Fly   365 VDLYL-CREVIN---------KEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVR 419
            .:.:| .|::||         .|.|:|            |.|...|             .|.:|:
Human    84 EEQHLRTRDIINVSNRYFNPSGEPLEL------------DSRFWEL-------------RDSIVQ 123

  Fly   420 MERETLRVIKYDLGIPLSYRFLRRYA--------RCAKVPMPTLTLARYILELSLMDYANISFSD 476
            .|...|||:::.:.....:::|..|.        |.:....|....|..:|..|......:.|..
Human   124 CELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQA 188

  Fly   477 SQMASAALFMALRMHG--GPGQL--DKQTW 502
            ..:|.|.|::||:::|  .|.::  :|..|
Human   189 QHIAVAVLYLALQVYGVEVPAEVEAEKPWW 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	26/134 (19%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	17/80 (21%)
CCNQ	NP_689487.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		CYCLIN_CCNM_CCNQ_rpt1	26..135	CDD:410237	29/140 (21%)
		CYCLIN_CCNM_CCNQ_rpt2	140..243	CDD:410238	17/79 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000