Protein Alignment CycB3 and CCNE2

DIOPT Version :10

• Sequence 1: NP_651303.2
• Gene: CycB3 / 42971
• FlyBaseID: FBgn0015625
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_477097.1
• Gene: CCNE2 / 9134
• HGNCID: 1590
• Length: 404
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 83/316 - (26%)
• Similarity: 133/316 - (42%)
• Gaps: 98/316 - (31%)

  Fly   250 RRSAKLQQKTEQQPQPLLLTLPETAPSQVVPI----------------------------PPV-- 284
            |||::||.|  |||||.....|:.|  |::..                            |||
Human     3 RRSSRLQAK--QQPQPSQTESPQEA--QIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPVLS 63

  Fly   285 -----------PEE---VEDFDR------KN------------WDDPFQVSHYAMDIFNYLK--- 314
                       |.:   ..||.|      ||            |....:|      ..|.||
Human    64 GGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEV------WLNMLKKES 122

  Fly   315 --VREAEFPI--ADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLY-LCREVI 374
              |.:..|.:  :|..|:       ||::|:||::||.|.:.|:.||.|||....|.: |.::.|
Human   123 RYVHDKHFEVLHSDLEPQ-------MRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI 180

  Fly   375 NKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYR 439
            ||..|||:|..:.|||.|.:|...|.:::|.|:.|||.:.::::|||...|:.:|::|.......
Human   181 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIIS 245

  Fly   440 FLRRYARC-AKVPMPTLTLARY----------ILELSLMDYANISFSDSQMASAAL 484
            :|..:.:. |....|.:.|.:|          :|:|.::...::.|....:.:|||
Human   246 WLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAAL 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_651303.2	CYCLIN_CCNB3_rpt1	290..431	CDD:410212	53/166 (32%)
		CYCLIN_CCNB3_rpt2	435..555	CDD:410214	11/61 (18%)
CCNE2	NP_477097.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		14/44 (32%)
		CYCLIN_CCNE2_rpt1	100..236	CDD:410283	47/148 (32%)
		CYCLIN_CCNE2_rpt2	240..338	CDD:410285	11/62 (18%)