DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB3 and CCNG2

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_004345.1	Gene:	CCNG2 / 901	HGNCID:	1593	Length:	344	Species:	Homo sapiens

Alignment Length:	154	Identity:	34/154 - (22%)
Similarity:	58/154 - (37%)	Gaps:	13/154 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 HYAMDIFNYLKV----------REAEFPIADYMPRQIH-LTTWMRTLLVDWMVEVQETFELNHET 357
            |..:.:...|.|          ||....:.:..|...: |...:|...|:.:..:...|....||
Human    12 HEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTET 76

  Fly   358 LYLAVKIVDLYLCREVINKEKLQLLGAAAFFIACKYDER--QPPLIEDFLYICDGAYNHDELVRM 420
            ..|||.|:|.:|....:..:.|..:|..:|.:|.:..|.  ..|...|.:.|........::.||
Human    77 FVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRM 141

  Fly   421 ERETLRVIKYDLGIPLSYRFLRRY 444
            |:.....:.|:|....:..||..|
Human   142 EKIISEKLHYELEATTALNFLHLY 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	29/137 (21%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	3/10 (30%)
CCNG2	NP_004345.1	CYCLIN_CCNG2	55..150	CDD:410287	22/94 (23%)
CCNG2	NP_004345.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	301..320
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810