Protein Alignment CycB3 and CCNA1

DIOPT Version :9

• Sequence 1: NP_001262934.1
• Gene: CycB3 / 42971
• FlyBaseID: FBgn0015625
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_003905.1
• Gene: CCNA1 / 8900
• HGNCID: 1577
• Length: 465
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 128/361 - (35%)
• Similarity: 188/361 - (52%)
• Gaps: 42/361 - (11%)

  Fly   195 PPTHNLAAPQVAAVKPVRRISNDFNKTEDSLYMSALE--DVSSCDSMRLSGNFEAARRRSAKLQQ 257
            ||....|.|.....:|.::   .|:     :||..||  |..|| |:|....||..    .::..
Human   115 PPAGKKALPDCGVQEPPKQ---GFD-----IYMDELEQGDRDSC-SVREGMAFEDV----YEVDT 166

  Fly   258 KTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDRKNWDDPFQVSHYAMDIFNYLKVREAEF-- 320
            .|.:.....||.....:|..|  ...:..:.||..... .|...|:.||.:|:.||  ||||.
Human   167 GTLKSDLHFLLDFNTVSPMLV--DSSLLSQSEDISSLG-TDVINVTEYAEEIYQYL--REAEIRH 226

  Fly   321 -PIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYL-CREVINKEKLQLLG 383
             |.|.||.:|..:|..|||:||||:|||.|.::|..|||||||..:|.:| |..|: :.||||:|
Human   227 RPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVL-RGKLQLVG 290

  Fly   384 AAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRRYARCA 448
            .||..:|.||:|..||.:::|:||.|..|...:|::||...|:|:.:||.:|.:.:||.:|.|..
Human   291 TAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQ 355

  Fly   449 KVPMPTLTLARYILELSLMDYAN--ISFSDSQMASAALFMALRMHGGPGQLDKQTWTSTLIYYTG 511
            .|.:.|..||:|:.||||:: |:  :.:..|.:|:||..:|      ...::|..|..||..:||
Human   356 GVCVRTENLAKYVAELSLLE-ADPFLKYLPSLIAAAAFCLA------NYTVNKHFWPETLAAFTG 413

  Fly   512 YQLADFAEIVTALNAGLHRK----PRATIKTIRNKY 543
            |.|   :|||..|:. ||:.    |....:.||.||
Human   414 YSL---SEIVPCLSE-LHKAYLDIPHRPQQAIREKY 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	60/128 (47%)
		Cyclin_C	435..555	CDD:281044	39/115 (34%)
CCNA1	NP_003905.1	Cyclin_N2	71..>145	CDD:293109	10/37 (27%)
		Cyclin_N	214..340	CDD:278560	60/128 (47%)
		Cyclin_C	342..459	CDD:281044	39/115 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820