DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB3 and CYCB2;4

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001323249.1	Gene:	CYCB2;4 / 843964	AraportID:	AT1G76310	Length:	459	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	122/523 - (23%)
Similarity:	209/523 - (39%)	Gaps:	139/523 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 DEEQSGV-GKKPTAQQLQALMDAKKQENLSVNVFGASKMTTRASSKVEDSVENCHKVLDKLEEAL 158
            ||.:.|| |  |..:|...|...|        |...:..|.||.|.:..::             :
plant     5 DENRHGVIG--PMNRQQGGLRGGK--------VIPTNGQTRRALSNINKNI-------------I 46

  Fly   159 ARPKPRPKAV--PAAKKTVLGEVQLPAMPNPMQIPVLLPPTHNLAA----------------PQV 205
            ..| ..|.||  |..:|..:...::|      .:||..|.|...||                |.:
plant    47 GAP-VYPCAVKRPFTEKNGICNKKIP------PVPVHRPVTRKFAAQLAENNLQIHKEETKKPDL 104

  Fly   206 AAVKPVRRI-----SNDFNK------TEDSLYMSALEDVSSCDSMRL--SGNFEAARRRSAKLQQ 257
            .:.:.:.||     ..|||:      ||     :.||::...:.:.:  |.:.:|
plant   105 ISNEALDRIITDVEEGDFNEPMFVQHTE-----AMLEEIDKMEGIEMQDSNDIDA---------- 154

  Fly   258 KTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDRKNWDDPFQVSHYAMDIFNYLKVREAEFPI 322
                                     .|.|.|.|.|..:.::|..|..|..||:.:.|..|....:
plant   155 -------------------------EVEESVMDIDSCDKNNPLSVVEYINDIYCFYKKNECRSCV 194

  Fly   323 -ADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLC-REVINKEKLQLLGAA 385
             .:||..|..:...||.:|.||::||...|||..|||||.:.::|.:|. .:.|.::||||:|..
plant   195 PPNYMENQHDINERMRGILFDWLIEVHYKFELMEETLYLTINLIDRFLAVHQHIARKKLQLVGVT 259

  Fly   386 AFFIACKYDERQPPLIEDFLYICDGAYNHDELVRM----------------------------ER 422
            |..:||||:|...|:::|.:.|.|.||...|::.|                            |:
plant   260 AMLLACKYEEVSVPVVDDLILISDKAYTRTEILDMVKSFTKSCPDYNHGCSALYVDDHYCVLQEK 324

  Fly   423 ETLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMDYANISFSDSQMASAALFMA 487
            .....::::..:|..|.|:||:.:.|:.......|:.:::||.|::|..:.::.||:|::|::.|
plant   325 LMANTLQFNFCLPTPYVFMRRFLKAAQSDKKLELLSFFMIELCLVEYEMLQYTPSQLAASAIYTA 389

  Fly   488 LRMHGGPGQLDKQTWTSTLIYYTGYQLADFAEIVTALNAGLHRKP-RATIKTIRNKYSHKIFHEV 551
            .....|     .:.|:.|..:::||......|....: .|||.|. ...:..:..||:...|...
plant   390 QSTLKG-----YEDWSKTSEFHSGYTEEALLECSRKM-VGLHHKAGTGKLTGVHRKYNTSKFGYA 448

  Fly   552 AKV 554
            |::
plant   449 ARI 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	45/154 (29%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	30/121 (25%)
CYCB2;4	NP_001323249.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880