DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycB3 and CYCA1;1

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_175077.1	Gene:	CYCA1;1 / 841014	AraportID:	AT1G44110	Length:	460	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	153/523 - (29%)
Similarity:	241/523 - (46%)	Gaps:	86/523 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 KRKADHSPIKNDKIKRSALGNLTNNVKIMTLHPAQDEEQ---SGVGKKPTAQQLQALMDAKKQEN 121
            :|.:..|..|:...||.|..:..|:||:|   ||..:::   |.:..:..|.:||. .|:....|
plant     8 RRSSFSSSTKSSLAKRQAPSSSENSVKLM---PAMTKKRAPLSNITNQKIASRLQN-SDSVHCSN 68

  Fly   122 LSVNVFGASKMTTRA--SSKVEDSVENCHKVLDKLEEALARPKPRPKAVPAAKKTVLGEVQLPAM 184
            .|..:..|..:...|  ||.::.|:.. |||                 ..:..|:..|.|.:...
plant    69 KSAKLKIAPSVCVNASFSSNLQQSIVP-HKV-----------------ASSPSKSDDGSVSMDET 115

  Fly   185 PNPMQIPVLLPPTHNLAAPQVAAVKPVRRISNDFNKTEDSLYMSALEDVSSCDSMRLSGNFEAAR 249
            .:         .:.:..:||      |..|.||......|:...||.::....:.....|:.:
plant   116 RS---------SSDSYKSPQ------VEYIENDDVSAVVSIERKALSNLFITPNSETIDNYCS-- 163

  Fly   250 RRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDRKNWDDPFQVSHYAMDIFNYLK 314
                          :.:|..:.:...:|:|.|          |..| .||...:.:|.||:.:|:
plant   164 --------------RDVLSDMKKMDKNQIVNI----------DSNN-GDPQLCATFACDIYKHLR 203

  Fly   315 VREA-EFPIADYMPR-QIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKE 377
            ..|| :.|..|||.| |..:.:.||.:||||::||.|.:.|..|||||.|..:|.||...||:::
plant   204 ASEAKKRPDVDYMERVQKDVNSSMRGILVDWLIEVSEEYRLVPETLYLTVNYIDRYLSGNVISRQ 268

  Fly   378 KLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLR 442
            ||||||.|...||.||:|...|.:|:|.||.|..|..||::.||.:.|..:|:::..|.:..|||
plant   269 KLQLLGVACMMIAAKYEEICAPQVEEFCYITDNTYLKDEVLDMESDVLNYLKFEMTAPTTKCFLR 333

  Fly   443 RYARCA----KVPMPTL-TLARYILELSLMDYANISFSDSQMASAALFMALRMHGGPGQLD--KQ 500
            |:.|.|    :.|:..| .:|.||.||||::|..:|.|.|.:|::|:|:|..:      ||  ::
plant   334 RFVRAAHGVHEAPLMQLECMANYIAELSLLEYTMLSHSPSLVAASAIFLAKYI------LDPTRR 392

  Fly   501 TWTSTLIYYTGYQLADFAEIVTALNAGLHRKPRATIKTIRNKYSHKIFHEVAK--VPLLTNQELF 563
            .|.|||.:||.|:..:....|..|.........:|:..:|.|||...:..|||  .|.:..||.|
plant   393 PWNSTLQHYTQYKAMELRGCVKDLQRLCSTAHGSTLPAVREKYSQHKYKFVAKKFCPSVIPQEFF 457

  Fly   564 QGN 566
            ..:
plant   458 NNS 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	57/126 (45%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	43/128 (34%)
CYCA1;1	NP_175077.1	CYCLIN_AtCycA_like_rpt1	187..322	CDD:410265	60/134 (45%)
CYCA1;1	NP_175077.1	CYCLIN_AtCycA-like_rpt2	326..440	CDD:410210	40/119 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2906
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920