DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB3 and CYCA2;1

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001332473.1	Gene:	CYCA2;1 / 832610	AraportID:	AT5G25380	Length:	443	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	140/518 - (27%)
Similarity:	223/518 - (43%)	Gaps:	99/518 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 RAKRKADHSPIKNDKIKRSALGNLTNNVKIMTLHPAQDEEQSGVGKKPTAQQLQALMDAKKQENL 122
            ||..|  |:..|.:.|..|.:.:  |||::    .....:..||...|:       ..|.|.|
plant     3 RASSK--HTNAKKEAISTSKIRD--NNVRV----TRSRAKALGVSNSPS-------KPAFKHE-- 50

  Fly   123 SVNVFGASKMTTRASSK--VEDSVENCHKVLDKLEEALARPKPRPKAVPAAKKTVLGEVQLPAMP 185
                   :|...|.|:|  ..|::..|::                     .::.||.:|
plant    51 -------TKRVARPSNKRMASDNITVCNQ---------------------KRRAVLKDV------ 81

  Fly   186 NPMQIPVLLPPTHNLAAPQVAA---VKPVRRISNDFNKTEDSLYMSALEDVSSCDSMRLSGNFEA 247
                       |:.||...::.   ||..:|...:..:.|:    ..|.||.. :..:|:.:...
plant    82 -----------TNTLAESIISTEGNVKACKRGGKETKQIEE----DGLVDVDG-EKSKLAEDLSK 130

  Fly   248 ARRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDRKNWDDPFQVSHYAMDIFNY 312
            .|...:.....::|:    |:...|...|.|...    .::.|.| ....||...|.||..|::.
plant   131 IRMVESLDASASKQK----LVDCAEEDRSDVTDC----VQIVDID-SGVQDPQFCSLYAASIYDS 186

  Fly   313 LKVREAE-FPIADYMPR-QIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVIN 375
            :.|.|.| .|...||.: |..:...||.:|:||:|||.|.::|..:||||.|.::|.::....|.
plant   187 INVAELEQRPSTSYMVQVQRDIDPTMRGILIDWLVEVSEEYKLVSDTLYLTVNLIDRFMSHNYIE 251

  Fly   376 KEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRF 440
            |:||||||.....||.||:|...|.:|:|.:|.|..|...|::.||.:.|..:.:.|.:|.:..|
plant   252 KQKLQLLGITCMLIASKYEEISAPRLEEFCFITDNTYTRLEVLSMEIKVLNSLHFRLSVPTTKTF 316

  Fly   441 LRRYARCA----KVPMPTLT-LARYILELSLMDYANISFSDSQMASAALFMALRMHGGPGQLDKQ 500
            |||:.|.|    |||:..:. ||.|..||:|.:|..:.|..|.:|::|:|:|      ...||:.
plant   317 LRRFIRAAQASDKVPLIEMEYLANYFAELTLTEYTFLRFLPSLIAASAVFLA------RWTLDQS 375

  Fly   501 T--WTSTLIYYTGYQLADFAEIVTALNAGLHRKPRATIKTIRNKYSHKIFHEVAKVPLLTNQE 561
            .  |..||.:||.|:.:.....|.|:.........:|:..|..||:.:.|..||   .||:.|
plant   376 NHPWNQTLQHYTRYETSALKNTVLAMEELQLNTSGSTLIAIHTKYNQQKFKRVA---TLTSPE 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	47/126 (37%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	40/126 (32%)
CYCA2;1	NP_001332473.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2906
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880