DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB3 and CYC1BAT

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_196233.1	Gene:	CYC1BAT / 830502	AraportID:	AT5G06150	Length:	445	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	129/512 - (25%)
Similarity:	218/512 - (42%)	Gaps:	118/512 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 MQTRAK--RKADHSPI--------KNDKIK-RSALGNLTNNVKIMTLHPAQDEEQSGVGK----K 104
            |.|||.  .:...:|:        ||..:| |.|||::.|.|.:..:       |.|..:    :
plant     1 MATRANVPEQVRGAPLVDGLKIQNKNGAVKSRRALGDIGNLVSVPGV-------QGGKAQPPINR 58

  Fly   105 PTAQQLQALMDAKKQ-ENLSVNVFGASKMTTRASSKVEDSVENCHKVLDKLEEALARPKPRPKAV 168
            |..:..:|.:.|..| |...:|  |.:|:                       .||. ||.:|.|.
plant    59 PITRSFRAQLLANAQLERKPIN--GDNKV-----------------------PALG-PKRQPLAA 97

  Fly   169 --PAAKKTVLGEVQLPAMPNPMQIPVLLPPTHNLAAPQVAAVKPVRRISNDFNKTEDSLYMSALE 231
              |.|::.|                    ...||...|  ..|||..|......|:..:.||
plant    98 RNPEAQRAV--------------------QKKNLVVKQ--QTKPVEVIETKKEVTKKEVAMS--- 137

  Fly   232 DVSSCDSMRLSGNFEAARRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDRKNW 296
                                     .|.::.....:|:....|...:|..|    ::.|.|..:.
plant   138 -------------------------PKNKKVTYSSVLSARSKAACGIVNKP----KIIDIDESDK 173

  Fly   297 DDPFQVSHYAMDIFNYLKVREAEFPIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLA 361
            |:......|..|::::.|..|.|.....||..|..:...||.:|:||::||...||||.|||||.
plant   174 DNHLAAVEYVDDMYSFYKEVEKESQPKMYMHIQTEMNEKMRAILIDWLLEVHIKFELNLETLYLT 238

  Fly   362 VKIVDLYLCREVINKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLR 426
            |.|:|.:|..:.:.|.:|||:|.:|..||.||:|..||.:.|.:|:.|.||:..:::.||:..|.
plant   239 VNIIDRFLSVKAVPKRELQLVGISALLIASKYEEIWPPQVNDLVYVTDNAYSSRQILVMEKAILG 303

  Fly   427 VIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMDYANISFSDSQMASAALFMA-LRM 490
            .:::.|.:|..|.||.|:.:.:........:..::.||.:|.|..::|..|.:|::|::.| ..:
plant   304 NLEWYLTVPTQYVFLVRFIKASMSDPEMENMVHFLAELGMMHYDTLTFCPSMLAASAVYTARCSL 368

  Fly   491 HGGPGQLDKQTWTSTLIYYTGY---QLADFAEIVTALNAGLHRKPRATIKTIRNKYS 544
            :..|      .||.||.::|||   ::.|.::::..|::   |...:.::.:..|||
plant   369 NKSP------AWTDTLQFHTGYTESEIMDCSKLLAFLHS---RCGESRLRAVYKKYS 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	48/124 (39%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	28/114 (25%)
CYC1BAT	NP_196233.1	CYCLIN_AtCycB-like_rpt1	162..307	CDD:410270	53/148 (36%)
CYC1BAT	NP_196233.1	CYCLIN_AtCycB-like_rpt2	312..428	CDD:410215	28/114 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880