DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB3 and CYCB2;2

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_195287.1	Gene:	CYCB2;2 / 829714	AraportID:	AT4G35620	Length:	429	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	119/522 - (22%)
Similarity:	215/522 - (41%)	Gaps:	136/522 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 IDPNVENMQTRAKRKADHSPIKNDKIKRSALGNLTNNVKIMTLHPAQDEEQSGVGKKPTAQQLQA 112
            :.|..|.:|...||..... ::..:..|.|||.:.:|:.....:|....::.|:     :|:.|.
plant    13 VKPITEILQDDDKRSRKFG-VEMKRQNRRALGVINHNLVGAKAYPCVVNKRRGL-----SQRKQE 71

  Fly   113 LMDAKKQENLSVNVFGASKMTTRASSKVEDSVENCHKVLDKLEEALARPKPRPKAVPAAKKTVLG 177
            ..|.||.::|                         |..:.:.:|...:.||.
plant    72 SCDKKKLDSL-------------------------HPSISRSQEETKKLKPS------------- 98

  Fly   178 EVQLPAMPNPMQIPVLLPPTHNLAAPQVAAVKPVRRISNDFNKTEDSLYMSALEDVSSCDSMRLS 242
                                                 .|:|.   |.:::...|:
plant    99 -------------------------------------GNEFG---DCIFIDEEEE---------- 113

  Fly   243 GNFEAARRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPEEVE-------------DFDRK 294
                       |.::.|..||.|:.|..|      .:...|:.||||             |.|..
plant   114 -----------KNEEVTLDQPMPMSLEEP------YIEFDPMEEEVEMEDMEEEQEEPVLDIDEY 161

  Fly   295 NWDDPFQVSHYAMDIFNYLKVRE--AEFPIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHET 357
            :.::......|..|::::.:..|  :..|: |||.:|..::..||.:|:||::||.:.|||.:||
plant   162 DANNSLAAVEYVQDLYDFYRKTERFSCVPL-DYMAQQFDISDKMRAILIDWLIEVHDKFELMNET 225

  Fly   358 LYLAVKIVDLYLCREVINKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMER 422
            |:|.|.::|.:|.::.:.::||||:|..|..:||||:|...|::||.:.|.|.||...:::.||:
plant   226 LFLTVNLIDRFLSKQAVARKKLQLVGLVALLLACKYEEVSVPIVEDLVVISDKAYTRTDVLEMEK 290

  Fly   423 ETLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMDYANISFSDSQMASAALFMA 487
            ..|..:::::.:|..|.||:|:.:.|:.......||.:::||:|:||..:.:..|.:|:.|::.|
plant   291 IMLSTLQFNMSLPTQYPFLKRFLKAAQSDKKLEILASFLIELALVDYEMVRYPPSLLAATAVYTA 355

  Fly   488 -LRMHGGPGQLDKQTWTSTLIYYTGYQLADFAEIVTALNAGLHRKPRATIKT-IRNKYSHKIFHE 550
             ..:||      ...|.||..::..|......|....: ..||:|......| :..|||...|..
plant   356 QCTIHG------FSEWNSTCEFHCHYSENQLLECCRRM-VRLHQKAGTDKLTGVHRKYSSSKFGY 413

  Fly   551 VA 552
            :|
plant   414 IA 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	45/126 (36%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	33/120 (28%)
CYCB2;2	NP_195287.1	COG5024	<157..412	CDD:227357	79/262 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880