Protein Alignment CycB3 and Ccnb3

DIOPT Version :10

• Sequence 1: NP_651303.2
• Gene: CycB3 / 42971
• FlyBaseID: FBgn0015625
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_001388082.1
• Gene: Ccnb3 / 317389
• RGDID: 1564367
• Length: 1404
• Species: Rattus norvegicus
• Alignment Length: 632
• Identity: 179/632 - (28%)
• Similarity: 282/632 - (44%)
• Gaps: 152/632 - (24%)

  Fly     6 ATTRAAITSGHHQLQQAVNPILGALGAATRKGLTRRAAATGNIDPNVENMQTRAKRKADHSP--- 67
            |..::.||......:..:.....|..|...|.|:....:...:....|.:.::.|.:|:...
  Rat   840 AIMKSLITEDESIKEAFIRSYTTATEAPAEKSLSLEETSINEVATLKEPLSSQEKHRAELVTVLK 904

  Fly    68 -----IKNDKIKRSALG---NLTNNVKIMTLHPAQDEEQSGVGKKPTAQQLQALMDAKKQENLSV 124
                 :||.:::|.||.   |..:||:.:........|:| .|::.|..:..||.:
  Rat   905 ELLVLVKNPRLERLALAFQENPPSNVETLLREVLALVEKS-TGEESTLNEPLALQE--------- 959

  Fly   125 NVFGASKMTTRASSKVEDSVENCHKVLDKLEEALARPKPRPKAVPAAKKTVLGEVQLPAMPNPMQ 189
                  |::|:|        |...|.|..||:.           |:.||
  Rat   960 ------KLSTKA--------ELSPKELLALEDN-----------PSFKK---------------- 983

  Fly   190 IPVLLPPTHNLAAPQVAAV---KP------VRRISNDFNK-TEDSLYMSAL-------------- 230
                       |:||.:..   ||      :.|:|..|.: :.||||...|
  Rat   984 -----------ASPQGSLTFDHKPDIEKDEITRMSFSFEEFSIDSLYEKVLALSEGFTTTEQLSF 1037

  Fly   231 EDVSSCDSMRL----------------------SGNFEAARRRSAKLQQKTEQQPQPLL------ 267
            .|:.:.|..::                      |..||:.:..|:        .|.|.|
  Rat  1038 TDLQNFDESKIVDEEDIFKSFFVFENENNPNLSSNGFESRKDNSS--------APMPSLEAFNSV 1094

  Fly   268 ------LTLPETAPSQV------VPIPPVPEEVEDFDRKNWDDPFQVSHYAMDIFNYLKVREAEF 320
                  ::..:::.|.:      |.|....:..|.|.::: .|....|.||.:||.|||.||.:|
  Rat  1095 MNSEPCVSATKSSQSSLGGKETEVIILDDSDTQESFVKED-SDLLLSSTYAKNIFIYLKEREEKF 1158

  Fly   321 PIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKEKLQLLGAA 385
            .:..||..|:.||:.||.:|||||||||..|.::|||||||||::|.||.:....|..|||||:.
  Rat  1159 IVTKYMDEQMELTSDMRAILVDWMVEVQANFRMSHETLYLAVKLMDRYLMKAQCEKNHLQLLGST 1223

  Fly   386 AFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRRYARCAKV 450
            |:.||.|::|..||.:.:|||||:..|...|:|.:||..|:.:.:|:.||::|.||||||.|...
  Rat  1224 AYMIAAKFEESYPPSLTEFLYICEDLYPKSEMVSLERNILKTLNFDINIPIAYHFLRRYASCIHA 1288

  Fly   451 PMPTLTLARYILELSLMDYANISFSDSQMASAALFMALRMHGGPGQLDKQTWTSTLIYYTGYQLA 515
            .|.||||:|:|.|::|.:|..|....|::|:|:..:||.|.      :.:....:|.|.||||||
  Rat  1289 SMKTLTLSRFICEMTLQEYDYIDERPSKLAAASFILALYMR------NLKDCVPSLEYSTGYQLA 1347

  Fly   516 DFAEIVTALNAGLHRKPRATIKTIRNKYSHKIFHEVAKVPLLTNQEL 562
            :...:|..||..|:.:.|..:|.:..|||.:.:.||||:|.|:.::|
  Rat  1348 ELHILVRKLNHLLNFRSRTVLKNVFEKYSEETYFEVAKIPPLSMKDL 1394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_651303.2	CYCLIN_CCNB3_rpt1	290..431	CDD:410212	66/140 (47%)
		CYCLIN_CCNB3_rpt2	435..555	CDD:410214	47/119 (39%)
Ccnb3	NP_001388082.1	CYCLIN_SF	1132..1269	CDD:477360	65/137 (47%)
		CYCLIN_SF	1273..1387	CDD:477360	47/119 (39%)