back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycB3 and Ccna1

DIOPT Version :10

Sequence 1:	NP_651303.2	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001011949.1	Gene:	Ccna1 / 295052	RGDID:	1310639	Length:	421	Species:	Rattus norvegicus

Alignment Length:	523	Identity:	146/523 - (27%)
Similarity:	215/523 - (41%)	Gaps:	156/523 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PNVENMQTRAKRKADHSPIKNDKIKRSALGNLTNNVKIMTLHPAQDEEQSGVGKKPTAQQLQALM 114
            |:...|.|||:       :..|..:|:.||.||.|          ::.:...|
  Rat    19 PDACQMLTRAQ-------LGQDPPQRTVLGVLTEN----------EQYRRACG------------ 54

  Fly   115 DAKKQENLSVNVFGASKMTTRASSKVEDSVENCHKVLDKLEEALARPKPRPKAVPAAKKTVLGEV 179
                ||..::..|..|              ||                    ..|||.|.||
  Rat    55 ----QEIATIRCFSGS--------------EN--------------------VFPAAGKKVL--- 78

  Fly   180 QLPAMPNPMQIPVLLPPTHNLAAPQVAAVKPVRRISNDFNKTEDSLYMS---------------- 228
                            |.:.::.|.               |....:||.
  Rat    79 ----------------PDNGVSEPA---------------KHGFDIYMDDPEQGDRDSCPGREGI 112

  Fly   229 ALEDVSSCDSMRLSGNFEAARRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDR 293
            ..|||...|:..|..:....      |...|   ..|:|  :..||.:|       .||..||.
  Rat   113 VFEDVYEVDTSMLKSDLHFL------LDFNT---VSPML--VDSTAHAQ-------SEEATDFG- 158

  Fly   294 KNWDDPFQVSHYAMDIFNYLKVREAEF---PIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNH 355
               .|...|:.||.:|..||  ||||.   |.|.||.:|..:|..||.:||||:|||.|.::|..
  Rat   159 ---SDVINVTEYAEEIHRYL--REAEVRHRPKAHYMRKQPDITEGMRAILVDWLVEVGEEYKLRT 218

  Fly   356 ETLYLAVKIVDLYL-CREVINKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVR 419
            |||||||..:|.:| |..|: :.||||:|.||..:|.||:|..||.:::|:||.|..|...:|:|
  Rat   219 ETLYLAVNFLDRFLSCMSVL-RGKLQLVGTAAILLASKYEEIYPPDVDEFVYITDDTYTKRQLLR 282

  Fly   420 MERETLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMDYAN--ISFSDSQMASA 482
            ||...|:|:.:||.:|.:.:||.:|.|...|.:.|..||:|:.||||:: |:  :.:..|.:|:|
  Rat   283 MEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCIRTENLAKYVAELSLLE-ADPFLKYLPSLVAAA 346

  Fly   483 ALFMALRMHGGPGQLDKQTWTSTLIYYTGYQLADFAEIVTALNAGLHRKPRATIKTIRNKY-SHK 546
            |..:|..:      :::..|..||..:|||.|.:....::.|:......|....:.||.|| :.|
  Rat   347 AYCLANYI------VNRHFWPETLAAFTGYSLNEIVPCLSELHKACLSIPHRPQQAIREKYKASK 405

  Fly   547 IFH 549
            ..|
  Rat   406 YLH 408

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.