Protein Alignment CycB3 and cdc13

DIOPT Version :10

• Sequence 1: NP_651303.2
• Gene: CycB3 / 42971
• FlyBaseID: FBgn0015625
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_001342891.1
• Gene: cdc13 / 2540880
• PomBaseID: SPBC582.03
• Length: 482
• Species: Schizosaccharomyces pombe
• Alignment Length: 562
• Identity: 160/562 - (28%)
• Similarity: 245/562 - (43%)
• Gaps: 128/562 - (22%)

  Fly    34 TRKGLTRR---AAATGNIDPN-VENMQTRAK---RKADHSPIKNDKI---------KRSALGNLT 82
            |.:.|||:   |...||.|.| ..|...|||   ..:::|.:...|.         ||.||.:::
pombe     2 TTRRLTRQHLLANTLGNNDENHPSNHIARAKSSLHSSENSLVNGKKATVSSTNVPKKRHALDDVS 66

  Fly    83 NNVKIMTLHPAQDEEQSGVGKKPTAQQLQALMDAKKQENLSVNVFGASKMTTRASSKVEDSVENC 147
            |      .|     .:.||   |.|           .:|.:|....||..|.||
pombe    67 N------FH-----NKEGV---PLA-----------SKNTNVRHTTASVSTRRA----------- 95

  Fly   148 HKVLDKLEEALARPKPRPKAVPAAKKTVLGEV---QLPAMPNPMQIPVLLPPTHNLAAPQVAAVK 209
                  |||....|....:  ||:||.....|   .:|::|..:........||.:.|
pombe    96 ------LEEKSIIPATDDE--PASKKRRQPSVFNSSVPSLPQHLSTKSHSVSTHGVDA------- 145

  Fly   210 PVRRISNDFNKTEDSLYMSALEDVSSCDSMRLSGNFEAARRRSAKLQQKTEQQPQPLLLTLPETA 274
                    |:|.:.::.....:||   |...:|.:.....|.|.:
pombe   146 --------FHKDQATIPKKLKKDV---DERVVSKDIPKLHRDSVE-------------------- 179

  Fly   275 PSQVVPIPPVPEEVEDFDRKNWDDPFQVSHYAMDIFNYLKVREAE-FPIADYMPRQIHLTTWMRT 338
                   .|..::.:|.|.::|.||..||.|.:|||.||...|.| .|...||.||..|...||.
pombe   180 -------SPESQDWDDLDAEDWADPLMVSEYVVDIFEYLNELEIETMPSPTYMDRQKELAWKMRG 237

  Fly   339 LLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKEKLQLLGAAAFFIACKYDERQPPLIED 403
            :|.||::||...|.|..|||:|||.|:|.:|...|.:..||||:|.||.|||.||:|...|.:::
pombe   238 ILTDWLIEVHSRFRLLPETLFLAVNIIDRFLSLRVCSLNKLQLVGIAALFIASKYEEVMCPSVQN 302

  Fly   404 FLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMD 468
            |:|:.||.|:.:|:::.||..|||::::|..|....||||.::.....:.|.|:|:|::|:.|:|
pombe   303 FVYMADGGYDEEEILQAERYILRVLEFNLAYPNPMNFLRRISKADFYDIQTRTVAKYLVEIGLLD 367

  Fly   469 YANISFSDSQMASAALFMALRMHG-GPGQLDKQTWTSTLIYYTGYQLADFAEIVTALNAGLHRKP 532
            :..:.:..||..:||:::|..|.| ||       |...|::|:||:......:|..:...| :||
pombe   368 HKLLPYPPSQQCAAAMYLAREMLGRGP-------WNRNLVHYSGYEEYQLISVVKKMINYL-QKP 424

  Fly   533 ---RATIKTIRNKYSHKIFHEVAKVPLLTNQELFQGNLDLNE 571
               .|..|    ||:.|.|   .|..|.....:.:.::.|.:
pombe   425 VQHEAFFK----KYASKKF---MKASLFVRDWIKKNSIPLGD 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_651303.2	CYCLIN_CCNB3_rpt1	290..431	CDD:410212	65/141 (46%)
		CYCLIN_CCNB3_rpt2	435..555	CDD:410214	37/123 (30%)
cdc13	NP_001342891.1	COG5024	5..454	CDD:227357	158/552 (29%)