Protein Alignment CycB3 and Ccnb1

DIOPT Version :10

• Sequence 1: NP_651303.2
• Gene: CycB3 / 42971
• FlyBaseID: FBgn0015625
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_741988.1
• Gene: Ccnb1 / 25203
• RGDID: 2291
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 464
• Identity: 128/464 - (27%)
• Similarity: 205/464 - (44%)
• Gaps: 120/464 - (25%)

  Fly   132 MTTRASSKVEDSVENCHKVLDKLEEALARPKPRPKAVPAAK-----KTVLGEV--------QLP- 182
            |..|.:...:.:.||..||      ::|..|..|.||.|:|     :|.||::        ::|
  Rat     1 MALRVTRNTKINTENKAKV------SMAGAKRVPVAVAASKPLLRSRTALGDIGNKVSEQSRIPL 59

  Fly   183 ---------------AMPNPM-QIPVLLPPTHNLAAPQVAAVKPVRRISNDFNKTEDSLYMSALE 231
                           |:|.|: ::||..|.. .|..|:...|..|:
  Rat    60 KKETKKLGSGTVTVKALPKPVDKVPVCEPEV-ELDEPEPEPVMEVK------------------- 104

  Fly   232 DVSSCDSMRLSGNFEAARRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPE---------- 286
                                         ..|:|:|:..|..:|.:.....|..|
  Rat   105 -----------------------------HSPEPILVDTPSPSPMETSGCAPAEEYLCQAFSDVI 140

  Fly   287 -EVEDFDRKNWDDPFQVSHYAMDIFNYLKVREAEFPIADYMPRQI---HLTTWMRTLLVDWMVEV 347
             .|.|.|..:..||...|.|..||:.||:..|.|..:   .|:.:   .:|..||.:|:||:::|
  Rat   141 LAVSDVDADDGGDPNLCSEYVKDIYAYLRQLEEEQSV---RPKYLLGREVTGNMRAILIDWLIQV 202

  Fly   348 QETFELNHETLYLAVKIVDLYLCREVINKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAY 412
            |..|.|..||:|:.|.|:|.::....:.|:.|||:|..|.|||.||:|..||.|.||.::.:..|
  Rat   203 QMKFRLLQETMYMTVSIIDRFMQDSCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTY 267

  Fly   413 NHDELVRMERETLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMDYANISFSDS 477
            ...::.:||.:.|||:.:.||.||...||||.::..:|.:...|||:|::|||::||..:.|:.|
  Rat   268 TKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELSMLDYDMVHFAPS 332

  Fly   478 QMASAALFMALRMHGGPGQLDKQTWTSTLIYYTGYQ-------LADFAEIVTALNAGLHRKPRAT 535
            |:|:.|..:||::      ||...||.||.:|..:.       :...|:.:..:|.||.:.
  Rat   333 QIAAGAFCLALKI------LDNGEWTPTLQHYLSHTEESLLPVMQHLAKNIVMVNRGLTKH---- 387

  Fly   536 IKTIRNKYS 544
             .||:|||:
  Rat   388 -MTIKNKYA 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_651303.2	CYCLIN_CCNB3_rpt1	290..431	CDD:410212	52/143 (36%)
		CYCLIN_CCNB3_rpt2	435..555	CDD:410214	39/117 (33%)
Ccnb1	NP_741988.1	Trypan_PARP	<59..>130	CDD:368653	16/119 (13%)
		CYCLIN_CCNB1_rpt1	157..285	CDD:410268	48/130 (37%)
		Interaction with CDK2. /evidence=ECO:0000250	159..167		3/7 (43%)
		Interaction with CDK2. /evidence=ECO:0000250	248..251		1/2 (50%)
		CYCLIN_SF	290..409	CDD:477360	39/117 (33%)