DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB3 and ccng1

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_021336635.1	Gene:	ccng1 / 171473	ZFINID:	ZDB-GENE-020322-1	Length:	313	Species:	Danio rerio

Alignment Length:	224	Identity:	46/224 - (20%)
Similarity:	94/224 - (41%)	Gaps:	28/224 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   280 PIPPVPEEVEDFDRKNWDDPF---------QVSHYAMDIFNYLKVREAEFPIADYMPRQIHLTTW 335
            |:|.:.::|.:....    ||         |.|.|...:.....:..|:       ...:.:|..
Zfish    11 PLPEMIDQVTETGAL----PFTVQLKSLLDQESRYQPKLCGLRVIESAQ-------DNGLRMTVK 64

  Fly   336 MRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKEKLQLLGAAAFFIACK--YDERQP 398
            :|...|..::.:...|....||...||.::|.:|....|..:.|..:|...|:||.|  .:|:..
Zfish    65 LRDYQVRELLSLTRFFGFCAETFSFAVNLLDRFLAVMKIQPKHLSCVGLCCFYIAVKTSEEEKNV 129

  Fly   399 PLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILE 463
            ||..|.:.|....:...:::|||:..|..:.:.:..|.:..|||.:.  :.:.....|.::.||.
Zfish   130 PLASDLIRISQNRFTVHDMMRMEKIILEKLNWKVKAPTALHFLRFFH--SHIQEKVDTESKKILN 192

  Fly   464 LSLMD----YANISFSDSQMASAALFMAL 488
            :..::    ..:.||:.:::..:.|.::|
Zfish   193 IERLEAQLKACHCSFTFTKLKPSLLALSL 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	27/126 (21%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	11/58 (19%)
ccng1	XP_021336635.1	Cyclin_N	31..163	CDD:306612	30/138 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810