DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB3 and CCNI

DIOPT Version :9

Sequence 1:	NP_001262934.1	Gene:	CycB3 / 42971	FlyBaseID:	FBgn0015625	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001335061.1	Gene:	CCNI / 10983	HGNCID:	1595	Length:	377	Species:	Homo sapiens

Alignment Length:	136	Identity:	37/136 - (27%)
Similarity:	60/136 - (44%)	Gaps:	10/136 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 MPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKEKLQLLGAAAFFIA 390
            ||...:::...|..::.|:.:::..|.|..||..||..::|.:|.....:.:.|..:..:.||:|
Human    34 MPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLA 98

  Fly   391 CK---YDERQP---PLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRRYARCAK 449
            .|   .|||.|   .|..|....|..:    |::||||..|..:.:||.......||..:...|.
Human    99 AKTVEEDERIPVLKVLARDSFCGCSSS----EILRMERIILDKLNWDLHTATPLDFLHIFHAIAV 159

  Fly   450 VPMPTL 455
            ...|.|
Human   160 STRPQL 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	31/112 (28%)
CycB3	NP_001262934.1	Cyclin_C	435..555	CDD:281044	5/21 (24%)
CCNI	NP_001335061.1	Cyclin_N	34..142	CDD:365896	30/111 (27%)
CCNI	NP_001335061.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	357..377
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810