DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH4 and ACA7

DIOPT Version :9

Sequence 1:	NP_651298.1	Gene:	CAH4 / 42965	FlyBaseID:	FBgn0039235	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_172287.1	Gene:	ACA7 / 837326	AraportID:	AT1G08080	Length:	275	Species:	Arabidopsis thaliana

Alignment Length:	259	Identity:	76/259 - (29%)
Similarity:	113/259 - (43%)	Gaps:	65/259 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFLVAR----SFAPINSGTRSHFG-------FNYDKQGR-----------DWNVKC--GERQSPI 41
            :|.||.    :...|:|...|| |       |||.|...           :|.: |  ||.||||
plant    10 IFFVALFSIFTIVSISSAASSH-GEVEDEREFNYKKNDEKGPERWGELKPEWEM-CGKGEMQSPI 72

  Fly    42 ALWSCNAITCNVPKLKFLN--YHKSLCDPLSVINNGLTVLMRIPKTVDGSRPSLCISTEGQQVFE 104
            .|  .|.....|..|..||  |:.|   ..::.|.|..:::   |..||:.   .|...|.: :|
plant    73 DL--MNERVNIVSHLGRLNRDYNPS---NATLKNRGHDIML---KFEDGAG---TIKINGFE-YE 125

  Fly   105 ADQLHFHWGSALSKGSEHCLDGNYYDGEVHIVHKNASYKSNKEAGLQPNGFAVLALFIRNLEDPN 169
            ..|||:|      ..|||.::|..:..|:|:||:..:.:......|...|.|  ..|||:||
plant   126 LQQLHWH------SPSEHTINGRRFALELHMVHEGRNRRMAVVTVLYKIGRA--DTFIRSLE--- 179

  Fly   170 IETPAMNMICKQVSSITKLDDSCPLEDSMALQD-LFASIDSQKYFTYQGSLTTPPCAEAVIWFV 232
                      |::..|.:::::   |.::.:.| ....|.|:||:.|.||||||||.:.|.|.|
plant   180 ----------KELEGIAEMEEA---EKNVGMIDPTKIKIGSRKYYRYTGSLTTPPCTQNVTWSV 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH4	NP_651298.1	alpha_CA	35..274	CDD:238200	62/201 (31%)
ACA7	NP_172287.1	alpha_CA_prokaryotic_like	49..270	CDD:239398	64/219 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.960