Protein Alignment CAH4 and CA6

DIOPT Version :9

• Sequence 1: NP_651298.1
• Gene: CAH4 / 42965
• FlyBaseID: FBgn0039235
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: XP_011540386.1
• Gene: CA6 / 765
• HGNCID: 1380
• Length: 324
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 100/303 - (33%)
• Similarity: 143/303 - (47%)
• Gaps: 68/303 - (22%)

  Fly     1 MFLVARSFAPINSGTRS-------HFGFNYDKQGRDWNVKCGERQSPIALWSCNAITCNVPKLKF 58
            :||:......::..|.|       |:..:|...|       |:|||||.| ....:..| |.||.
Human    14 LFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACG-------GQRQSPINL-QRTKVRYN-PSLKG 69

  Fly    59 LNY--HKSLCDPLSVINNGLTVLMRIPKTV-----DGSRPSLCISTEGQQVFEADQLHFHWGSAL 116
            ||.  :::......::|||.||.:.:|.|:     ||:            |:.|.|:|||||.|.
Human    70 LNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGT------------VYIAQQMHFHWGGAS 122

  Fly   117 SK--GSEHCLDGNYYDGEVHIVHKNASYKSNKEAGLQPNGFAVLALFIRNLEDP----------- 168
            |:  ||||.:||..:..|:||||.|:.|||...|...|:|.||||.|:.....|
Human   123 SEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISH 187

  Fly   169 --NIETPAMNMICKQVSSITKLDDSCPLEDSMALQDLFASIDSQKYFTYQGSLTTPPCAEAVIWF 231
              ||:.|.      |.:::|.||          :||:... :.|.|:||.||||||||.|.|.||
Human   188 LANIKYPG------QRTTLTGLD----------VQDMLPR-NLQHYYTYHGSLTTPPCTENVHWF 235

  Fly   232 VFPTPLDVPK-ELWKHFWQLRDSRDQRVLNTYRELQDGHDRPV 273
            |....:.:.: ::||....|.|.|::.:.|.||..|..:.|.|
Human   236 VLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVV 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH4	NP_651298.1	alpha_CA	35..274	CDD:238200	93/262 (35%)
CA6	XP_011540386.1	alpha_CA_VI	35..283	CDD:239399	96/282 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145752
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		otm41271
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750