Protein Alignment CAH4 and CA4

DIOPT Version :9

• Sequence 1: NP_651298.1
• Gene: CAH4 / 42965
• FlyBaseID: FBgn0039235
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: XP_005257696.1
• Gene: CA4 / 762
• HGNCID: 1375
• Length: 336
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 91/315 - (28%)
• Similarity: 139/315 - (44%)
• Gaps: 50/315 - (15%)

  Fly     3 LVARSFAPINSGTRSHFGFNYDKQGRD--------WNVKC-GERQSPIALWSCNA-ITCNVPKLK 57
            |:|.|.|..::...||:.:....:..:        |...| .:|||||.:.:..| :...:.:..
Human     7 LLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFF 71

  Fly    58 FLNYHKSLCDPLSVINNGLTVLMRIPKTVD---GSRPSLCISTEGQQVFEADQLHFHWGSALSKG 119
            |..|.|.  ...:|.|||.:|:|.:.....   |..|:         .::|.|||.||.....||
Human    72 FSGYDKK--QTWTVQNNGHSVMMLLENKASISGGGLPA---------PYQAKQLHLHWSDLPYKG 125

  Fly   120 SEHCLDGNYYDGEVHIVH--KNASYKSNKEAGLQPNGFAVLALFI--------------RNLEDP 168
            |||.|||.::..|:||||  :..:.::.|||....:..||||..:              |..:||
Human   126 SEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEIGRMNWPPPLAPCRLSQDP 190

  Fly   169 NIETPA-------MNMICKQVSSITKLDDSCPLEDSMALQDLFASIDSQKYFTYQGSLTTPPCAE 226
            ::...|       ...:.:.:|:|.|.:.|..:.:|..|..|......:.||.|.||||||.|.|
Human   191 SLPFQAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDE 255

  Fly   227 AVIWFVFPTPLDVPKELWKHFWQ-LRDSRDQRV--LNTYRELQDGHDRPVYRSKA 278
            .|:|.||..|:.:.:|....|.| |...::|.|  .:..|.||....|.|.:|.|
Human   256 KVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGA 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH4	NP_651298.1	alpha_CA	35..274	CDD:238200	80/268 (30%)
CA4	XP_005257696.1	alpha_CA_IV_XV_like	48..307	CDD:239391	81/269 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145720
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.810