Protein Alignment CAH4 and CA4

DIOPT Version :10

• Sequence 1: NP_651298.1
• Gene: CAH4 / 42965
• FlyBaseID: FBgn0039235
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: XP_005257696.1
• Gene: CA4 / 762
• HGNCID: 1375
• Length: 336
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 91/315 - (28%)
• Similarity: 139/315 - (44%)
• Gaps: 50/315 - (15%)

  Fly     3 LVARSFAPINSGTRSHFGFNYDKQGRD--------WNVKC-GERQSPIALWSCNA-ITCNVPKLK 57
            |:|.|.|..::...||:.:....:..:        |...| .:|||||.:.:..| :...:.:..
Human     7 LLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFF 71

  Fly    58 FLNYHKSLCDPLSVINNGLTVLMRIPKTVD---GSRPSLCISTEGQQVFEADQLHFHWGSALSKG 119
            |..|.|.  ...:|.|||.:|:|.:.....   |..|:         .::|.|||.||.....||
Human    72 FSGYDKK--QTWTVQNNGHSVMMLLENKASISGGGLPA---------PYQAKQLHLHWSDLPYKG 125

  Fly   120 SEHCLDGNYYDGEVHIVH--KNASYKSNKEAGLQPNGFAVLALFI--------------RNLEDP 168
            |||.|||.::..|:||||  :..:.::.|||....:..||||..:              |..:||
Human   126 SEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEIGRMNWPPPLAPCRLSQDP 190

  Fly   169 NIETPA-------MNMICKQVSSITKLDDSCPLEDSMALQDLFASIDSQKYFTYQGSLTTPPCAE 226
            ::...|       ...:.:.:|:|.|.:.|..:.:|..|..|......:.||.|.||||||.|.|
Human   191 SLPFQAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDE 255

  Fly   227 AVIWFVFPTPLDVPKELWKHFWQ-LRDSRDQRV--LNTYRELQDGHDRPVYRSKA 278
            .|:|.||..|:.:.:|....|.| |...::|.|  .:..|.||....|.|.:|.|
Human   256 KVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGA 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH4	NP_651298.1	alpha_CA	35..274	CDD:238200	80/268 (30%)
CA4	XP_005257696.1	alpha_CA_IV_XV_like	48..307	CDD:239391	81/269 (30%)