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Protein Alignment CAH4 and CA1

DIOPT Version :9

Sequence 1:	NP_651298.1	Gene:	CAH4 / 42965	FlyBaseID:	FBgn0039235	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_001122301.1	Gene:	CA1 / 759	HGNCID:	1368	Length:	261	Species:	Homo sapiens

Alignment Length:	245	Identity:	65/245 - (26%)
Similarity:	102/245 - (41%)	Gaps:	33/245 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FGFNYDKQG-RDWN----VKCGERQSPIALWSCNAITCNVPKLKFLNYHKSLCDPLSVINNGLTV 78
            :|:: ||.| ..|:    :..|..|||:.:.:..            ..|.:...|:||..|..|.
Human     6 WGYD-DKNGPEQWSKLYPIANGNNQSPVDIKTSE------------TKHDTSLKPISVSYNPATA 57

  Fly    79 --LMRIPKTV-----DGSRPSLCISTEGQQVFEADQLHFHWGSALSKGSEHCLDGNYYDGEVHIV 136
              ::.:..:.     |....|:.........:...|.||||||....||||.:||..|..|:|:.
Human    58 KEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVA 122

  Fly   137 HKN-ASYKSNKEAGLQPNGFAVLALFIRNLEDPNIETPAMNMICKQVSSITKLDDSCPLEDSMAL 200
            |.| |.|.|..||..:.:|.||:.:.::..|    ..|.:..:...:.:|.......|..:....
Human   123 HWNSAKYSSLAEAASKADGLAVIGVLMKVGE----ANPKLQKVLDALQAIKTKGKRAPFTNFDPS 183

  Fly   201 QDLFASIDSQKYFTYQGSLTTPPCAEAVIWFVFPTPLDVPKELWKHFWQL 250
            ..|.:|:|   ::||.||||.||..|:|.|.:....:.|..|....|..|
Human   184 TLLPSSLD---FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSL 230

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.