DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CAH4 and Car10

DIOPT Version :9

Sequence 1:NP_651298.1 Gene:CAH4 / 42965 FlyBaseID:FBgn0039235 Length:279 Species:Drosophila melanogaster
Sequence 2:NP_001348636.1 Gene:Car10 / 72605 MGIID:1919855 Length:328 Species:Mus musculus


Alignment Length:286 Identity:74/286 - (25%)
Similarity:131/286 - (45%) Gaps:45/286 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 LVARSFAPINSGTRSHFGFNYDKQGRDWNV-KCGERQSPIALWSCNAITCNVPKLKFLNYHKSLC 66
            :|..||.|:    .|.:|.    ....||: ..|:||||:     |..|.::....||.      
Mouse    38 VVQGSFVPV----PSFWGL----VNSAWNLCSVGKRQSPV-----NIETSHMIFDPFLT------ 83

  Fly    67 DPLSVINNGLTVLMRIPKTVDGSRPSLCISTE-------GQQVF--EADQLHFHWGSALSKGSEH 122
             ||.:...|..|...:..|  |...||.:..|       |...:  ..:::..|:||..|:||||
Mouse    84 -PLRINTGGRKVSGTMYNT--GRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEH 145

  Fly   123 CLDGNYYDGEVHIVHKNAS-YKSNKEAGLQPNGFAVLALFIRNLEDPNIETPAMNMICKQ--VSS 184
            .|:|..:.|||.::|.|.. |.:..||...|||..|:::||:..:..|   |.:|.:..:  ::.
Mouse   146 LLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSN---PFLNRMLNRDTITR 207

  Fly   185 ITKLDDSCPLEDSMALQDLFASIDSQKYFTYQGSLTTPPCAEAVIWFVFPTPLDVPKELWKHFWQ 249
            ||..:|:..|: .:.:::|:.  ::..:.||.||:|.|||.|...|.:...|:.:.:........
Mouse   208 ITYKNDAYLLQ-GLNIEELYP--ETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRL 269

  Fly   250 LRDSRDQRVL----NTYRELQDGHDR 271
            |..::..::.    :.:|.:|..::|
Mouse   270 LSQNQPSQIFLSMSDNFRPVQPLNNR 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CAH4NP_651298.1 alpha_CA 35..274 CDD:238200 66/253 (26%)
Car10NP_001348636.1 alpha_CARP_X_XI_like 46..302 CDD:239395 70/278 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167835820
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3338
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1377476at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.750

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