Protein Alignment CAH4 and PTPRG

DIOPT Version :10

• Sequence 1: NP_651298.1
• Gene: CAH4 / 42965
• FlyBaseID: FBgn0039235
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: XP_016862450.1
• Gene: PTPRG / 5793
• HGNCID: 9671
• Length: 1485
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 75/303 - (24%)
• Similarity: 125/303 - (41%)
• Gaps: 68/303 - (22%)

  Fly    31 NVKCGER-QSPIALWSCNA-ITCNVPKLKFLNYHKSLCDPLSVINNGLTV--LMRIPKTVDGSRP 91
            :|.||.| ||||.:....| :.....:|:...:.....:...:.|.|.||  |::....|.|:
Human    75 SVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGA-- 137

  Fly    92 SLCISTEGQQVFEADQLHFHWG-SALSKGSEHCLDGNYY--------DGEVHIVHKN-------- 139
                ...|:  |:|:::.|||| |..|.||||.::|..:        .|::.::...
Human   138 ----GLPGR--FKAEKVEFHWGHSNGSAGSEHSINGRRFPVEAEDARGGDIMLMLSQGMRFILLG 196

  Fly   140 ------------ASYKSNKEAGLQPNGF-------------AVLALFIRNLEDPNIETPAMNMIC 179
                        .:|:|.:.....|:.|             ..:|:|.:  ..|. :..|::.|.
Human   197 LKKEQFEERKSWTTYQSMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQ--VSPR-DNSALDPII 258

  Fly   180 KQVSSITKLDDSCPLEDSMALQDLF-ASIDSQKYFTYQGSLTTPPCAEAVIWFVFPTPLDVPKEL 243
            ..:..:...:....| |...|:||. ||:.|  |:.|.||||||||:|.|.|.||..|:.:....
Human   259 HGLKGVVHHEKETFL-DPFVLRDLLPASLGS--YYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQ 320

  Fly   244 WKHFWQLRDSRDQ-------RVLNTYRELQDGHDRPVYRSKAK 279
            .:.|:.:..:..|       .:.|.:|..|..|||.|.:|..:
Human   321 LEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHDRVVSKSAVR 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH4	NP_651298.1	alpha_CA	35..274	CDD:238200	71/292 (24%)
PTPRG	XP_016862450.1	alpha_CARP_receptor_like	67..359	CDD:239396	74/297 (25%)
		FN3	388..478	CDD:238020
		PHA03169	<584..>742	CDD:223003
		R-PTPc-G-1	888..1161	CDD:350505
		R-PTP-G-2	1245..1449	CDD:350508