Protein Alignment CAH4 and CA10

DIOPT Version :9

• Sequence 1: NP_651298.1
• Gene: CAH4 / 42965
• FlyBaseID: FBgn0039235
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_001076002.1
• Gene: CA10 / 56934
• HGNCID: 1369
• Length: 328
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 74/286 - (25%)
• Similarity: 131/286 - (45%)
• Gaps: 45/286 - (15%)

  Fly     3 LVARSFAPINSGTRSHFGFNYDKQGRDWNV-KCGERQSPIALWSCNAITCNVPKLKFLNYHKSLC 66
            :|..||.|:    .|.:|.    ....||: ..|:||||:     |..|.::....||.
Human    38 VVQGSFVPV----PSFWGL----VNSAWNLCSVGKRQSPV-----NIETSHMIFDPFLT------ 83

  Fly    67 DPLSVINNGLTVLMRIPKTVDGSRPSLCISTE-------GQQVF--EADQLHFHWGSALSKGSEH 122
             ||.:...|..|...:..|  |...||.:..|       |...:  ..:::..|:||..|:||||
Human    84 -PLRINTGGRKVSGTMYNT--GRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEH 145

  Fly   123 CLDGNYYDGEVHIVHKNAS-YKSNKEAGLQPNGFAVLALFIRNLEDPNIETPAMNMICKQ--VSS 184
            .|:|..:.|||.::|.|.. |.:..||...|||..|:::||:..:..|   |.:|.:..:  ::.
Human   146 LLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSN---PFLNRMLNRDTITR 207

  Fly   185 ITKLDDSCPLEDSMALQDLFASIDSQKYFTYQGSLTTPPCAEAVIWFVFPTPLDVPKELWKHFWQ 249
            ||..:|:..|: .:.:::|:.  ::..:.||.||:|.|||.|...|.:...|:.:.:........
Human   208 ITYKNDAYLLQ-GLNIEELYP--ETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRL 269

  Fly   250 LRDSRDQRVL----NTYRELQDGHDR 271
            |..::..::.    :.:|.:|..::|
Human   270 LSQNQPSQIFLSMSDNFRPVQPLNNR 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH4	NP_651298.1	alpha_CA	35..274	CDD:238200	66/253 (26%)
CA10	NP_001076002.1	alpha_CARP_X_XI_like	46..302	CDD:239395	70/278 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145753
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750