DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH4 and ca14

DIOPT Version :9

Sequence 1:	NP_651298.1	Gene:	CAH4 / 42965	FlyBaseID:	FBgn0039235	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_001315073.1	Gene:	ca14 / 567897	ZFINID:	ZDB-GENE-051030-57	Length:	373	Species:	Danio rerio

Alignment Length:	258	Identity:	84/258 - (32%)
Similarity:	120/258 - (46%)	Gaps:	30/258 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KCGE-RQSPIALWSCNAITCNVPKL---KFLNYHKSLCDPLSVINNGLTVLMRIPKTVD-GSRPS 92
            :||. .|||:.:.:..  |.:.|.|   :.:.|::....|..:.|||.||.|.:|..:. |..||
Zfish    43 ECGGFNQSPVNVDTSQ--TLHDPTLIPVQPMGYNQPGRRPFILSNNGHTVQMTLPHWMGVGGLPS 105

  Fly    93 LCISTEGQQVFEADQLHFHWGS--ALSKGSEHCLDGNYYDGEVHIVHKNAS-YKSNKEAGLQPNG 154
                     .:.|.|||.|||:  .::.||||.::|.....|:||||.|.. |.:..||.:|.||
Zfish   106 ---------HYSAVQLHLHWGNGVGIATGSEHTINGQSTSAELHIVHYNTEVYANLSEAMMQKNG 161

  Fly   155 FAVLALFIRNLEDPNIETPAMNMICKQVSSITKLDDSCPLEDSMALQDLFASIDSQKYFTYQGSL 219
            .|||.:.|...|:.|   .|...|...:..|........: .|..||.|.....|| ||.|.|||
Zfish   162 LAVLGILIETGEEVN---QAYGSIFNYLGRIRYAGQKVAI-PSFDLQSLLPENLSQ-YFRYNGSL 221

  Fly   220 TTPPCAEAVIWFVFPTPLDVP-KELWKHFWQLRDSRDQR-----VLNTYRELQDGHDRPVYRS 276
            |||||.|:|:|.:|...:.:. .:|.|....|..|:.:.     :.:.||..|..:.|.|..|
Zfish   222 TTPPCHESVLWTIFNERVKISHSQLLKLETVLYSSKAEEEEPTILQDNYRATQPLNHRTVLSS 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH4	NP_651298.1	alpha_CA	35..274	CDD:238200	81/252 (32%)
ca14	NP_001315073.1	alpha_CA	33..285	CDD:294017	84/258 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579142
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750