DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH4 and Ptprg

DIOPT Version :9

Sequence 1:	NP_651298.1	Gene:	CAH4 / 42965	FlyBaseID:	FBgn0039235	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_599183.2	Gene:	Ptprg / 171357	RGDID:	620774	Length:	1442	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	72/263 - (27%)
Similarity:	120/263 - (45%)	Gaps:	28/263 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NVKC-GERQSPIALWSCNA-ITCNVPKLKFLNYHKSLCDPLSVINNGLTV--LMRIPKTVDGSRP 91
            :|.| |..||||.:...:| :.....:|:...:.....:...:.|.|.||  |::....|.|:
  Rat    75 SVSCGGSHQSPIDILDHHARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGA-- 137

  Fly    92 SLCISTEGQQVFEADQLHFHWG-SALSKGSEHCLDGNYYDGEVHIVHKNASYKSNKEAGLQPNG- 154
                ...|:  |:|:::.|||| |..|.||||.::|..:..|:.|...|.....:.:..:..|.
  Rat   138 ----GLPGR--FKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRI 196

  Fly   155 FAVLALFIRNLEDPNIETPAMNMICKQVSSITKLDDSCPLEDSMALQDLF-ASIDSQKYFTYQGS 218
            ...:|:|.:  ..|. :..|::.|...:..:...:....| |...|:||. ||:.|  |:.|.||
  Rat   197 IGAMAIFFQ--VSPR-DNSALDPIIHGLKGVVHHEKETFL-DPFVLRDLLPASLGS--YYRYTGS 255

  Fly   219 LTTPPCAEAVIWFVFPTPLDVPKELWKHFWQLRDSRDQ-------RVLNTYRELQDGHDRPVYRS 276
            ||||||:|.|.|.||..|:.:.....:.|:.:..:..|       .:.|.:|..|..:||.|.:|
  Rat   256 LTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDRVVSKS 320

  Fly   277 KAK 279
            ..:
  Rat   321 AVR 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH4	NP_651298.1	alpha_CA	35..274	CDD:238200	68/251 (27%)
Ptprg	NP_599183.2	alpha_CARP_receptor_like	67..319	CDD:239396	71/257 (28%)
		FN3	348..438	CDD:238020
		R-PTPc-G-1	845..1118	CDD:350505
		R-PTP-G-2	1202..1406	CDD:350508
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810