Protein Alignment Nct and AT3G52640

DIOPT Version :10

• Sequence 1: NP_001262932.1
• Gene: Nct / 42964
• FlyBaseID: FBgn0039234
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_974419.1
• Gene: AT3G52640 / 824430
• AraportID: AT3G52640
• Length: 705
• Species: Arabidopsis thaliana
• Alignment Length: 759
• Identity: 169/759 - (22%)
• Similarity: 296/759 - (38%)
• Gaps: 169/759 - (22%)

  Fly     9 SIWLLILSYGATIAQGERTRD---KMYEPIGGASCFRRLNGTHQTGCSSTYSGSVGVLHLINVEA 70
            ||..|.||....|...|...|   .||..:.|..|.|.||.:.:.|||:.....| |..:|.::
plant    19 SILPLHLSLADEITSIESVPDLQKLMYVAVDGFPCVRLLNLSGEIGCSNPGINKV-VAPIIKLK- 81

  Fly    71 DLEFLLSSPPSPPYAPMIPPH-----------LFTRNNLMRLKEAGPKNISVVLLINRTN---QM 121
            |::            .::.||           .|||   :....:....|..||:.:.:|   ::
plant    82 DVK------------DLVQPHTILVTADEMEDFFTR---VSTDLSFASKIGGVLVESGSNFQQKL 131

  Fly   122 KQFSHELNCPN-QYSGLNSTSETCDASNPAKN----WNPWGTGLLHEDFPFPIYYIAD-----LD 176
            |.||.:...|. |:|             |.:|    ||...:.::..::.||:|.:::     :.
plant   132 KGFSPDKRFPQAQFS-------------PYENVEYKWNSAASSIMWRNYNFPVYLLSESGISAVH 183

  Fly   177 QVTKLEKCFQDFNNHNYETHALRSLCAVEVKSFMSAAVNTEVCMRRTNFINNLGGSKYCDPLEGR 241
            ::...:|.     .|...|..:.....| :::..:...|:|.|::...          |.||.|.
plant   184 EILSKKKM-----KHGTYTSDVAEFNMV-METTKAGTHNSEACLQEGT----------CLPLGGY 232

  Fly   242 NVYATLYPRKPAIENNLETVHTNEKFILVTCRLDTTTMFDGVGLGAMDSLMGFAVF--------- 297
            :|:::|.|...:..||.:.|      :|....:||.:.|.....||...:.|....
plant   233 SVWSSLPPISVSSSNNRKPV------VLTVASMDTASFFRDKSFGADSPISGLVALLGAVDALSR 291

  Fly   298 -THVAYLLKQLLPPQSKDLHNVLFVTFNGESYDYIGSQRFVYDMEKLQFPTESTGTPPIAFDNID 361
             ..::.|.|||           :|:...||::.|:||:||:::::     ..|.....::..:|:
plant   292 VDGISNLKKQL-----------VFLVLTGETWGYLGSRRFLHELD-----LHSDAVAGLSNTSIE 340

  Fly   362 FMLDIGTL-----DDISNIKLHALNGTTLAQQILERLNNYAKSPRYGFNLNIQSEMSAH--LPPT 419
            .:|:||::     ..|:....|....:::....|:.| ..|:......|:.|.|..:|:  :||:
plant   341 TVLEIGSVGKGLSGGINTFFAHKTRVSSVTNMTLDAL-KIAQDSLASKNIKILSADTANPGIPPS 404

  Fly   420 SAQSFLRRDPNFNALILNARPT---NKYYHSIYDD----ADNVDFTYANTSKDFTQLTEVNDFKS 477
            |..:|:|::|..:|::|....|   ||:|||..||    :.::.|:...:...|..|.......:
plant   405 SLMAFMRKNPQTSAVVLEDFDTNFVNKFYHSHLDDLCKKSHSLSFSSFRSKPHFALLIPFWCCIA 469

  Fly   478 LNPDSLQMKVRNVSSIVAMALY-----QTITGKEYTGTKVANPLMADEFLYCFL---QSADCPLF 534
            .|.:|  ..|...:|:||..||     ...|.....|:...|....:|.|.|.|   ....|.|.
plant   470 ANINS--SSVVAAASVVARTLYILASDNKDTSNSALGSIHVNASFVEELLTCLLACEPGLSCNLV 532

  Fly   535 KAASYPGSQLTNLPPMRYISVLGGSQESSGYTYRLLGYL--LSQL-------QPDIHRDNCTDL- 589
            |....|    ||..|..|..|:.|...|..|    |||:  :|:.       :..:.:.|.|.:
plant   533 KDYISP----TNTCPGNYAGVILGEPSSKPY----LGYVGDVSRFLWNFLADKTSVQKGNTTSVC 589

  Fly   590 ---------PLHYFAGFNNIGECRLTTQNYSHALSPAFLIDGYDW---------SSGMYS-TWTE 635
                     .:...|..|..|.|.::|..|..|.|.....:...|         |.||.. .|||
plant   590 SKGVCSKTDEVCIKAESNKEGTCVVSTTRYVPAYSTRLKYNDGAWTILPQNSSDSMGMVDPVWTE 654

  Fly   636 STWSQFSARIFLRPSNVHQVTTLSVGIVVLIISFCLVYIISSRS 679
            |.|......::....:.:....|..||.|..:::  :.|::::|
plant   655 SNWDTLRVHVYTVQHSAYDNAVLVAGITVTTLAY--IGILAAKS 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nct	NP_001262932.1	M28_Nicastrin	42..639	CDD:349877	150/681 (22%)
AT3G52640	NP_974419.1	M28_Nicastrin	48..658	CDD:349877	152/688 (22%)