DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7006 and Nip7

DIOPT Version :9

Sequence 1:	NP_651296.1	Gene:	CG7006 / 42963	FlyBaseID:	FBgn0039233	Length:	180	Species:	Drosophila melanogaster
Sequence 2:	NP_079667.2	Gene:	Nip7 / 66164	MGIID:	1913414	Length:	180	Species:	Mus musculus

Alignment Length:	179	Identity:	117/179 - (65%)
Similarity:	145/179 - (81%)	Gaps:	0/179 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKRLSDERAKILFEHLSKYIGTNVKHLIDRPDGTYCFREHKDRVYYVSERILKLSECFGYKQLVC 65
            |:.|::|..:::||.::||||.|::.|:||||||||||.|.||||||||.:|||:......:||.
Mouse     1 MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEMMLKLAANISGDKLVS 65

  Fly    66 VGTCFGKFSKTNKLKFHITALYYLAPYAQYKVWVKPSFEQQFLYGNHIPKTGLGRITENAGQYQG 130
            :|||||||:||:|.:.|:|||.||||||:|||||||..||.||||||:.|:||||||||..||||
Mouse    66 LGTCFGKFTKTHKFRLHVTALDYLAPYAKYKVWVKPGAEQSFLYGNHVLKSGLGRITENTSQYQG 130

  Fly   131 VVVYSMNDLPLGFGVLARSTTDCKTADPMTTVCFHQSDIGEYIRAEDTL 179
            ||||||.|:||||||.|:||.||:..|||..|.|||:|||||:|.|:||
Mouse   131 VVVYSMADIPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETL 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7006	NP_651296.1	PUA	1..177	CDD:294405	114/175 (65%)
Nip7	NP_079667.2	NIP7	1..176	CDD:224293	114/174 (66%)
		N-terminal domain. /evidence=ECO:0000250	1..92		52/90 (58%)
		C-terminal domain. /evidence=ECO:0000250	93..180		63/87 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850196
Domainoid	1	1.000	129	1.000	Domainoid score	I5269
eggNOG	1	0.900	-	-		E1_COG1374
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56743
Inparanoid	1	1.050	257	1.000	Inparanoid score	I3140
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53780
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005084
OrthoInspector	1	1.000	-	-		oto95437
orthoMCL	1	0.900	-	-		OOG6_102224
Panther	1	1.100	-	-	LDO	PTHR23415
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R812
SonicParanoid	1	1.000	-	-		X3604
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790