DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7006 and nip7

DIOPT Version :9

Sequence 1:	NP_651296.1	Gene:	CG7006 / 42963	FlyBaseID:	FBgn0039233	Length:	180	Species:	Drosophila melanogaster
Sequence 2:	NP_001018426.1	Gene:	nip7 / 553616	ZFINID:	ZDB-GENE-050522-256	Length:	180	Species:	Danio rerio

Alignment Length:	179	Identity:	123/179 - (68%)
Similarity:	145/179 - (81%)	Gaps:	0/179 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKRLSDERAKILFEHLSKYIGTNVKHLIDRPDGTYCFREHKDRVYYVSERILKLSECFGYKQLVC 65
            |:.|:||..|.:||.||||||.|:|.||||||||||||.|.|||||:||:||||:......:||.
Zfish     1 MRPLTDEETKTMFEKLSKYIGENIKLLIDRPDGTYCFRLHNDRVYYMSEKILKLATNVSRDKLVS 65

  Fly    66 VGTCFGKFSKTNKLKFHITALYYLAPYAQYKVWVKPSFEQQFLYGNHIPKTGLGRITENAGQYQG 130
            ||||||||:||.|.:.|||||.:|||||::||||||..||.|||||||.|:||||||||..:|||
Zfish    66 VGTCFGKFTKTQKFRLHITALDFLAPYAKFKVWVKPGSEQSFLYGNHIMKSGLGRITENTDKYQG 130

  Fly   131 VVVYSMNDLPLGFGVLARSTTDCKTADPMTTVCFHQSDIGEYIRAEDTL 179
            |:||||.|:||||||.||:|.:|:..|||..|.|||:|||||||:||||
Zfish   131 VLVYSMADVPLGFGVAARTTQECRKVDPMAIVVFHQADIGEYIRSEDTL 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7006	NP_651296.1	PUA	1..177	CDD:294405	119/175 (68%)
nip7	NP_001018426.1	NIP7	1..177	CDD:224293	119/175 (68%)
		N-terminal domain. /evidence=ECO:0000250	1..92		59/90 (66%)
		C-terminal domain. /evidence=ECO:0000250	93..180		62/87 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596069
Domainoid	1	1.000	125	1.000	Domainoid score	I5434
eggNOG	1	0.900	-	-		E1_COG1374
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56743
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3102
OMA	1	1.010	-	-		QHG53780
OrthoDB	1	1.010	-	-		D1405073at2759
OrthoFinder	1	1.000	-	-		FOG0005084
OrthoInspector	1	1.000	-	-		oto40581
orthoMCL	1	0.900	-	-		OOG6_102224
Panther	1	1.100	-	-	LDO	PTHR23415
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R812
SonicParanoid	1	1.000	-	-		X3604
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800