DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Esp and SULTR1;2

DIOPT Version :9

Sequence 1:	NP_001189282.1	Gene:	Esp / 42962	FlyBaseID:	FBgn0013953	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001321366.1	Gene:	SULTR1;2 / 844135	AraportID:	AT1G78000	Length:	653	Species:	Arabidopsis thaliana

Alignment Length:	634	Identity:	169/634 - (26%)
Similarity:	281/634 - (44%)	Gaps:	85/634 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 EPNGSSNSVG----SQGSKEFILTEDGKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILG 89
            :|:.:.:.||    ....|:|:.|     .|.|....|..|.:....:.:.| ...|....|:..
plant    22 KPSPTRHKVGIPPKQNMFKDFMYT-----FKETFFHDDPLRDFKDQPKSKQF-MLGLQSVFPVFD 80

  Fly    90 WLPKYNSQDAVGDLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMG 154
            |...|..:...|||::|:|:....|||.:.||.:|.|...||||:|||...||..:||.:|:.:|
plant    81 WGRNYTFKKFRGDLISGLTIASLCIPQDIGYAKLANLDPKYGLYSSFVPPLVYACMGSSRDIAIG 145

  Fly   155 PSAIVALL--TYQAAQGSWQKS--------VLLCLLSGIVELLMGLFGLGFLIDFVSGPVSSGFT 209
            |.|:|:||  |...|:.....|        ......:||.|..:|.|.|||||||:|.....||.
plant   146 PVAVVSLLLGTLLRAEIDPNTSPDEYLRLAFTATFFAGITEAALGFFRLGFLIDFLSHAAVVGFM 210

  Fly   210 SAVSLIILTSQIQSVLGIT--AKGNTFVEIWTQVFHNIEHTRAGDTVL-GLTCIVILLLMRSLSS 271
            ...::.|...|::..|||.  .|....:.:...||....|.....|:| |.:.:..||..:.:.
plant   211 GGAAITIALQQLKGFLGIKKFTKKTDIISVLESVFKAAHHGWNWQTILIGASFLTFLLTSKIIG- 274

  Fly   272 CRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLHTEEHGAPFRVVGEIPPGLPS 336
                           :...|:.|:...| ..|.|:|.....|:...::.|.  ::|..:..|:..
plant   275 ---------------KKSKKLFWVPAIA-PLISVIVSTFFVYITRADKQGV--QIVKHLDQGINP 321

  Fly   337 IQLPPTSLTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFANGK--PVDASQELI 399
            ........|.:..:.|:..|            ||..:::|.|.:||.:.||..|  .:|.::|::
plant   322 SSFHLIYFTGDNLAKGIRIG------------VVAGMVALTEAVAIGRTFAAMKDYQIDGNKEMV 374

  Fly   400 AIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFLTPYFYFIPRPTLA 464
            |:|..|:..|....:..||:.||.|||..:|.:|.:|||....:|::.||||||.|.:.|...||
plant   375 ALGMMNVVGSMSSCYVATGSFSRSAVNFMAGCQTAVSNIIMSIVVLLTLLFLTPLFKYTPNAILA 439

  Fly   465 AIIISAVVFMIEVKVVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVGLNVIFILYHAARPK 529
            ||||:||:.:|:::....:::..|.|.:..:|.|...:.:.:|.|:||.|.::...||....||:
plant   440 AIIINAVIPLIDIQAAILIFKVDKLDFIACIGAFFGVIFVSVEIGLLIAVSISFAKILLQVTRPR 504

  Fly   530 LSTELL----------TTQSGVEYSM------ITPDRCLIFPSVDYVRNLVNK------QSIR-Q 571
              |.:|          ..|...|.:|      |..|..:.|.:.:|||..:.:      :.:: .
plant   505 --TAVLGNIPRTSVYRNIQQYPEATMVPGVLTIRVDSAIYFSNSNYVRERIQRWLHEEEEKVKAA 567

  Fly   572 NVP----VVIDASHVYGADFTTATVIDSLISDFNQRGQLLFFYNLKPSI 616
            ::|    ::|:.|.|...|.:....::.|.....:|...|...|..|.:
plant   568 SLPRIQFLIIEMSPVTDIDTSGIHALEDLYKSLQKRDIQLILANPGPLV 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	156/570 (27%)
		HCO3_cotransp	103..520	CDD:304903	127/431 (29%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913	17/89 (19%)
SULTR1;2	NP_001321366.1	sulP	77..641	CDD:273284	157/573 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
OMA	1	1.010	-	-		QHG55446
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		mtm1058
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870