Protein Alignment Esp and Slc26a5

DIOPT Version :9

• Sequence 1: NP_001189282.1
• Gene: Esp / 42962
• FlyBaseID: FBgn0013953
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_110467.1
• Gene: Slc26a5 / 83819
• RGDID: 69334
• Length: 744
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 156/618 - (25%)
• Similarity: 279/618 - (45%)
• Gaps: 144/618 - (23%)

  Fly    34 SNSVGSQGSKEFILTEDGKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILGWLPKYNSQD 98
            ::|:|.:..:.|..|.  |||                       |..::..|||..|||.|..::
  Rat    39 TDSIGDKLKQAFTCTP--KKV-----------------------RNIIYMFLPITKWLPAYKFKE 78

  Fly    99 AV-GDLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALL 162
            .| ||||:||:.|:..:||.||:|.:|.:|..:|||:||....:|.|.|:.:.:.:||.|:::|:
  Rat    79 YVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLM 143

  Fly   163 T-----------------YQAAQGSWQKSVL-------LCLLSGIVELLMGLFGLGFLIDFVSGP 203
            .                 ..|..|:..:..|       :.|||||::..:|:...||:..:::.|
  Rat   144 IGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEP 208

  Fly   204 VSSGFTSAVSLIILTSQIQSVLGITAKGNTFVEIWTQVFHNIEHTRAGDTVLGLTCIVILLLMRS 268
            :..|||:|.::.:.||.::.:.|:..|  .:..|::.|:               :.:.:|..:::
  Rat   209 LVRGFTTAAAVHVFTSMLKYLFGVKTK--RYSGIFSVVY---------------STVAVLQNVKN 256

  Fly   269 LSSCRIGP--------VDEKECSSFQRAVNKI---------LWIVGTARNAILVVVCCIMGYMLH 316
            |:.|.:|.        :..||.:  :|...|:         ..::||..:|         |:.||
  Rat   257 LNVCSLGVGLMVFGLLLGGKEFN--ERFKEKLPAPIPLEFFAVVMGTGISA---------GFNLH 310

  Fly   317 TEEHGAPFRVVGEIPPGLPSIQLPPTSLTAN-ETSNGVAEGFVEMVHSMGSGLVVIPLISLMENI 380
             |.:...  |||.:|.||    |||    || :||         :.|.:....:.|.::.....|
  Rat   311 -ESYSVD--VVGTLPLGL----LPP----ANPDTS---------LFHLVYVDAIAIAIVGFSVTI 355

  Fly   381 AICKAFAN--GKPVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGL 443
            ::.|..||  |..||.:|||||:|..|...|..|.|..:.:|||..|...:|.:|.|:...:.
  Rat   356 SMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLAS-- 418

  Fly   444 VMIALLFLTPYFYF--IPRPTLAAIIISAV--VFMIEVKVVKPMWRSKKSDLVPGVGTFVACLVL 504
            :||.|:.|...|.|  :|:..|:||:|..:  :|| :...:...||:.|.:|...:.|||:.|.|
  Rat   419 LMILLVILATGFLFESLPQAVLSAIVIVNLKGMFM-QFSDLPFFWRTSKIELTIWLTTFVSSLFL 482

  Fly   505 PLEWGILIGVGLNVIFILYHAARPKLSTELLTTQSGVEYSMI--TPDRCLIFPSVD---YVRNLV 564
            .|::|::..|.:.::.::|....|             .|:::  .||.. ::..:|   .|:.:.
  Rat   483 GLDYGLITAVIIALLTVIYRTQSP-------------SYTVLGQLPDTD-VYIDIDAYEEVKEIP 533

  Fly   565 NKQSIRQNVPVVIDASHVYGADFTTATVIDSLI 597
            ..:..:.|.|:....|.:|.:.....|.::..|
  Rat   534 GIKIFQINAPIYYANSDLYSSALKRKTGVNPAI 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Esp	NP_001189282.1	sulP	86..615	CDD:273284	147/566 (26%)
		HCO3_cotransp	103..520	CDD:304903	125/464 (27%)
		STAS_SulP_like_sulfate_transporter	545..623	CDD:132913	10/58 (17%)
Slc26a5	NP_110467.1	sulP	66..709	CDD:273284	147/566 (26%)
		STAS_SulP_like_sulfate_transporter	526..694	CDD:132913	7/41 (17%)
		STAS	589..>683	CDD:279997
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	720..744

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.710